Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Nicotinamide
CAS Number: 98-92-0
Alias: Niacinamide, Vitamin B3 amide, 3-Pyridinecarboxamide
Chemical Full Name: Pyridine-3-carboxamide
Molecular Formula: C6H6N2O
Molecular Weight: 122.12
EINECS: 202-713-4
Structural Information
- Structure Type: Pyridine vitamin amide derivative
- Structural Features: Pyridine ring with carboxamide group at the 3-position; core component of coenzyme NAD/NADP, participates in human body energy metabolism cycle
- Characteristic: Water-soluble B vitamin, stable amide structure, no vasodilation side effects compared with nicotinic acid
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Odorless, slightly bitter taste
- Melting Point: 128–131 °C
- Solubility: Freely soluble in water and ethanol; slightly soluble in glycerol; insoluble in ether, benzene
- Stability: Stable under normal sealed storage; resistant to light, heat and weak acid/alkali; will hydrolyze to nicotinic acid under strong acid high temperature condition
Synthesis & Applications
Production Method
Oxidation of 3-methylpyridine to nicotinic acid, then amidation with ammonia, recrystallization and drying to obtain finished product.
Main Applications
- Pharmaceutical raw material: Vitamin B3 supplement for oral tablets, injections, compound vitamin preparations
- Food additive: Nutritional fortifier for dairy, beverage, cereal, health food
- Feed additive: Nutritional supplement for livestock, poultry and aquaculture feed
- Cosmetic raw material: Classic whitening repair ingredient, inhibits melanin transfer, improves skin barrier, reduces oil secretion
Safety & Storage Instructions
GHS Hazard Classification
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation from dust inhalation
Personal Protection
Dust mask, chemical splash goggles, nitrile gloves; operate in ventilated environment to avoid dust inhalation.
Storage Condition
Hermetically sealed light-proof container, cool dry warehouse; isolate strong acid and strong alkaline substances.
Transportation
General food/pharmaceutical raw material solid; waterproof packaging to prevent moisture caking.
Quality Specifications
- Purity (Titration/HPLC): 99.0%–101.0%
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
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