Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Inosine
CAS Number: 58-63-9
Alias: Hypoxanthosine, 9-β-D-Ribofuranosylhypoxanthine
Chemical Full Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,9-dihydro-6H-purin-6-one
Molecular Formula: C10H12N4O5
Molecular Weight: 268.23
EINECS: 200-390-4
Structural Information
- Structure Type: Natural purine nucleoside pharmaceutical intermediate
- Structural Features: Purine hypoxanthine base linked with β-D-ribose glycosidic bond; participates in human intracellular energy metabolism and nucleic acid synthesis; improves cell activity and tissue repair capacity
- Characteristic: Nucleoside raw material for energy supply medicine, widely used in liver and cardiac auxiliary drugs
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Odorless, slight bitter taste
- Melting Point: 218–220 °C (decomposes)
- Specific Rotation: [α]D2? ?48° ~ ?52° (c=1, water)
- Solubility: Soluble in hot water, slightly soluble in cold water; insoluble in ethanol, acetone, ether
- Stability: Stable under light-proof sealed storage; hydrolyzed into hypoxanthine and ribose under strong acid heating; stable under weak acid and neutral conditions
Synthesis & Applications
Production Method
Biological fermentation of yeast extract, separation, decolorization, ion exchange purification and recrystallization.
Main Applications
- Pharmaceutical Raw Material: Core raw material for inosine tablets/injections, auxiliary treatment for hepatitis, myocarditis, leukopenia
- Health Food Additive: Anti-fatigue, improve immunity functional food nutrient fortifier
- Biochemical Reagent: Standard nucleoside for molecular biology research, cell culture medium additive
- Nucleic Acid Derivative Intermediate: Precursor for synthetic antiviral nucleoside drugs
Safety & Storage Instructions
GHS Hazard Classification
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation from dust inhalation
Personal Protection
Dust mask, chemical splash goggles, nitrile gloves; operate in ventilated environment to avoid long-term dust inhalation.
Storage Condition
Hermetically sealed light-proof plastic-lined paper drum, cool dry warehouse ≤25℃; isolate strong acid substances, prevent moisture absorption and caking.
Transportation
General pharmaceutical solid powder; waterproof and light-shield packaging during transit.
Quality Specifications
- Purity (HPLC): ≥99.0%
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 58-63-9 |
| Product Name | Inosine |
| Synonym | Hypoxanthosine |
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 |
| Appearance | White crystalline powder |
| Melting Point | 218–220℃ (decomposition) |
| Core Advantage | Natural purine nucleoside, energy metabolism pharmaceutical intermediate |
| Storage Rule | Light-proof sealed dry storage, separate from strong acid |
| Hazard Property | Low toxicity, dust mildly irritates skin, eyes and respiratory tract |
| Main Usage | Hepatocardiac auxiliary drug raw material, anti-fatigue health food additive, biochemical research reagent |
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