Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: Methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate
- Aliases: Albendazole, ABZ
- CAS Number: 54965-21-8
- EINECS: N/A
- Molecular Formula: C12H15N3O2S
- Molecular Weight: 269.33
- Chemical Classification: Veterinary & human antiparasitic API, benzimidazole bulk drug
- Core Advantages
Broad-spectrum benzimidazole antiparasitic active ingredient. Effective against nematodes, cestodes and trematodes; inhibits parasite tubulin polymerization to block nutrient absorption and kill parasites. High purity meets USP/EP veterinary and human pharmaceutical standards, widely used in oral tablet, suspension formulations for human and livestock parasite treatment.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Solubility: Slightly soluble in DMSO, chloroform; practically insoluble in water, ethanol, aliphatic alkanes
- Melting Point: 208–212 °C (decomposes)
- Hygroscopy: Non-hygroscopic under normal dry storage
- Crystal Character: Uniform fine crystalline powder with good formulation dispersibility
2.2 Chemical Properties
- Benzimidazole Heterocyclic Skeleton: Contains carbamate and propylthio functional groups responsible for antiparasitic bioactivity
- Acid & Alkali Stability: Stable under neutral and weak acidic environments; hydrolyzes under strong alkaline heating
- Thermal Stability: Decomposes above melting point without sublimation
- Photostability: Sensitive to intense UV light; long-term light exposure causes discoloration and activity loss
- Compatibility: Compatible with common pharmaceutical solid excipients; incompatible with strong oxidants and concentrated alkali
3. Main Application Fields
3.1 Pharmaceutical API (Core Usage)
Raw material for human oral antiparasitic tablets and suspensions, indicated for intestinal worm, tapeworm and hydatid disease infections; also core veterinary drug for cattle, sheep, pig and poultry deworming preparations.
3.2 Pharmacological Research Standard
Reference standard for antiparasitic drug efficacy testing in pharmaceutical laboratories and veterinary research institutions.
3.3 Veterinary Drug Intermediate
Finished bulk active ingredient directly used for compound deworming veterinary formulation production.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 54965-21-8 |
| Molecular Formula | C12H15N3O2S |
| Molecular Weight | 269.33 |
| Appearance | White to off-white crystalline powder |
| Melting Range | 208–212 °C (decompose) |
| HPLC Assay | Pharma Grade ≥99.0%; Veterinary Grade ≥98.5% |
| Single Maximum Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.50% |
| Moisture Content (KF) | ≤0.30% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg light-proof aluminum foil lined fiber drum with nitrogen seal |
| Sample Package | 10g / 100g / 1kg sealed light-proof aluminum foil bag |
| Storage Requirements | Hermetic, light-proof cool dry warehouse ≤25℃; isolate humid air, intense light and oxidants |
| Transportation Rule | Non-hazardous antiparasitic API; light-proof waterproof packaging mandatory during transit |
| Shelf Life | 36 months under intact nitrogen-sealed light-proof packaging |
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