Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: 4-chloro-2-benzofuran-1,3-dione
- Aliases: 4-Chlorophthalic anhydride, 4-Chloro-1,2-benzenedicarboxylic anhydride
- CAS Number: 118-45-6
- EINECS: 204-254-0
- Molecular Formula: C8H3ClO3
- Molecular Weight: 182.56
- Chemical Classification: Halogenated aromatic anhydride intermediate, dye & pigment raw material, epoxy curing agent precursor
- Core Advantages
Contains anhydride reactive group and para-chloro substituent. Undergoes imidization, esterification, amidation and ring-opening addition reactions. Key monomer for high-performance polyimide resins, solvent dyes, fluorescent pigments and pharmaceutical heterocyclic derivatives, with stable halogenated aromatic skeleton for heat-resistant material production.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White to off-white crystalline flakes
- Odor: Slightly pungent anhydride odor
- Solubility: Soluble in hot ethanol, acetone, toluene, DMF; slightly soluble in cold organic solvents; insoluble in water
- Melting Point: 96–99 °C
- Hygroscopy: Moderately hygroscopic, hydrolyzes gradually in humid air
- Crystal Feature: Flaky crystals with good filtration performance after recrystallization
2.2 Chemical Properties
- Cyclic Anhydride Functional Group: Rapid ring-opening hydrolysis in water to form 4-chlorophthalic acid; reacts with amines, alcohols to generate imides, esters
- Aryl Chloride Reactivity: C-Cl bond supports nucleophilic substitution for introducing various functional groups
- Acid & Alkali Stability: Stable under dry neutral conditions; fully hydrolyzed under aqueous alkaline heating
- Thermal Stability: Stable below 220 °C; sublimates at high temperature without obvious decomposition
- Photostability: Stable under indoor light; long-term strong UV exposure causes slight discoloration
- Compatibility: Compatible with anhydrous polar solvents and polycondensation monomers; incompatible with water, aqueous alkalis and strong nucleophilic protic solvents
3. Main Application Fields
3.1 Polyimide Resin Monomer (Core Usage)
Key raw material for synthesizing halogenated high-temperature resistant polyimide films and coatings; improves thermal stability and dielectric performance of finished polymer materials.
3.2 Dye & Fluorescent Pigment Intermediate
Building block for solvent dyes, fluorescent whitening agents and vat dyes; the chloro substituent enhances color fastness and light resistance of pigments.
3.3 Pharmaceutical Synthetic Building Block
Precursor for preparing chlorinated phthalimide-based antibacterial and anti-inflammatory small molecule drugs via imidization derivatization.
3.4 Epoxy Resin Curing Agent Intermediate
Raw material for synthesizing modified anhydride curing agents for high-temperature epoxy composite systems.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 118-45-6 |
| Molecular Formula | C8H3ClO3 |
| Molecular Weight | 182.56 |
| Appearance | White to off-white crystalline flakes |
| Melting Range | 96–99 °C |
| HPLC Chemical Purity | Synthesis Grade ≥98.0%; Electronic Grade ≥99.5% |
| Free Acid (4-Chlorophthalic Acid) | ≤0.20% |
| Moisture Content (KF) | ≤0.20% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg light-proof fiber drum lined with aluminum foil |
| Sample Package | 10g / 100g / 1kg sealed light-proof aluminum foil bag |
| Storage Requirements | Hermetic, moisture-proof cool dry warehouse ≤25℃; isolate humid air, water and alkaline substances |
| Transportation Rule | General aromatic anhydride intermediate, non-hazardous goods; moisture-proof waterproof packaging mandatory during transit |
| Shelf Life | 24 months under intact sealed light-proof packaging |
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