Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: 4-Hydroxyphenyl β-D-glucopyranoside
- Aliases: Hydroquinone O-β-D-glucoside, β-Arbutin
- CAS Number: 497-76-7
- EINECS: 207-850-3
- Molecular Formula: C12H16O7
- Molecular Weight: 272.25
- Chemical Classification: Natural glycoside skin whitening raw material, cosmetic active ingredient, plant extract derivative
- Core Advantages
Natural phenolic glycoside extracted from bearberry leaves. Inhibits tyrosinase activity to block melanin synthesis, delivers mild skin brightening and spot-fading effects without strong irritation. High purity cosmetic grade complies with international cosmetic safety standards, widely used in whitening serum, cream, mask and sunscreen formulations; also applied as biological research substrate.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White fine crystalline powder
- Odor: Odorless
- Solubility: Freely soluble in hot water, methanol, ethanol; slightly soluble in cold water; insoluble in aliphatic hydrocarbons
- Melting Point: 198–202 °C
- Specific Optical Rotation [α]D20: -64° ~ -68° (c=3, ethanol)
- Hygroscopy: Slightly hygroscopic under high humidity
- UV Character: Absorbs UV at 280 nm wavelength
2.2 Chemical Properties
- Glycoside Structure: Glucose glycosidic bond linked to hydroquinone; slow enzymatic hydrolysis releases hydroquinone under biological conditions
- Acid & Alkali Stability: Stable under neutral and weak acidic cosmetic formula pH (4.5–7); glycosidic bond hydrolyzes under strong acid heating
- Thermal Stability: Stable below 100°C; long-term heating above 120°C triggers partial decomposition
- Photostability: Sensitive to strong UV light; antioxidant additive required to avoid discoloration in finished cosmetic products
- Compatibility: Compatible with most cosmetic humectants, emulsifiers and plant extracts; incompatible with strong oxidants, heavy metal ions and concentrated mineral acids
3. Main Application Fields
3.1 Cosmetic Whitening Raw Material (Core Usage)
Key active ingredient for skin brightening, freckle-lightening and uniform tone care products; suppresses melanin formation to improve dull and pigmented skin safely.
3.2 Biological Laboratory Reagent
Tyrosinase enzyme activity detection substrate for melanin metabolism research in biochemistry labs.
3.3 Natural Preservative Auxiliary
Auxiliary antibacterial agent in mild natural personal care formulations.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 497-76-7 |
| Molecular Formula | C12H16O7 |
| Molecular Weight | 272.25 |
| Appearance | White fine crystalline powder |
| Melting Range | 198–202 °C |
| HPLC Purity | Cosmetic Grade ≥99.0%; Research Grade ≥99.5% |
| Free Hydroquinone | ≤10 ppm |
| Moisture Content (KF) | ≤0.30% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg light-proof aluminum foil lined fiber drum |
| Sample Package | 10g / 100g / 1kg sealed light-proof aluminum foil bag |
| Storage Requirements | Hermetic, light-proof cool dry warehouse ≤25℃; isolate humid air, intense light and oxidizing substances |
| Transportation Rule | Non-hazardous cosmetic active raw material; light-proof waterproof packaging mandatory during transit |
| Shelf Life | 24 months under intact sealed light-proof packaging |
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