Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: Poly(α-D-glucopyranosyl) polysaccharide
- Aliases: Dextran polymer, Dextran polysaccharide
- CAS Number: 9004-54-0
- EINECS: 232-677-5
- Molecular Formula: (C6H10O5)n
- Molecular Weight: Variable, customizable molecular weight grades ranging from 1kDa to 2000kDa
- Chemical Classification: Biodegradable natural polysaccharide polymer, pharmaceutical excipient, biological separation medium raw material
- Core Advantages
Water-soluble linear glucose polysaccharide produced by microbial fermentation. Excellent biocompatibility, low immunogenicity, adjustable molecular weight. Widely applied as plasma volume expander raw material, chromatographic stationary phase precursor, sustained-release drug carrier and food thickener, compliant with USP/EP/FCC specifications.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White or off-white amorphous powder
- Odor: Odorless
- Solubility: Freely soluble in hot water; partially soluble in cold water; insoluble in ethanol, acetone and aliphatic hydrocarbons
- Solution Character: Forms clear viscous aqueous solution, viscosity positively correlated with molecular weight
- Hygroscopy: Moderately hygroscopic under high humidity environment
- Optical Property: Exhibits optical rotation in aqueous solution
2.2 Chemical Properties
- α-1,6 Glycosidic Bond Main Chain: Contains scattered α-1,3 branched linkages; degradable by dextranase enzyme
- Acid & Alkali Stability: Stable under neutral and weak acidic conditions; glycosidic bond hydrolyzes under strong acid heating to produce glucose fragments
- Thermal Stability: Stable below 100°C; long-term heating above 120°C triggers partial thermal degradation and viscosity reduction
- Photostability: Stable under indoor ambient light; intense UV irradiation accelerates molecular chain breakage
- Compatibility: Compatible with neutral inorganic salts and most water-soluble pharmaceutical excipients; incompatible with concentrated strong acids and heavy metal precipitants
3. Main Application Fields
3.1 Pharmaceutical Raw Material (Core Usage)
Raw material for intravenous plasma substitute injection preparations; molecular weight fractionated dextran used as blood volume expanding agent for shock treatment; also applied as sustained-release matrix and stabilizer for protein biological formulations.
3.2 Biochemical Chromatography Medium
Precursor for cross-linked Sephadex gel packing materials used in gel filtration protein separation and molecular weight calibration experiments.
3.3 Food Industry Additive
Biodegradable thickener, stabilizer and dietary fiber supplement for beverage and baked food systems.
3.4 Biomedical Research Reagent
Standard molecular weight marker for gel electrophoresis and size-exclusion chromatography calibration.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 9004-54-0 |
| Molecular Formula | (C6H10O5)n |
| Appearance | White amorphous powder |
| Molecular Weight Range | Customizable 1 kDa – 2000 kDa |
| Water Content (KF) | ≤5.00% |
| Reducing Sugar | ≤0.20% |
| Heavy Metals (Pb) | ≤10 ppm (Pharma/Food Grade) |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg woven bag with inner PE moisture-proof liner |
| Sample Package | 1kg / 5kg sealed aluminum foil bag |
| Storage Requirements | Hermetic moisture-proof cool dry warehouse ≤25℃; isolate humid air and strong acidic substances |
| Transportation Rule | Non-hazardous polysaccharide polymer; waterproof and moisture-proof packaging required during transit |
| Shelf Life | 24 months under intact sealed packaging |
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