Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
- Aliases: Mannitol, D-Mannite
- CAS Number: 69-65-8
- EINECS: 200-711-8
- Molecular Formula: C6H14O6
- Molecular Weight: 182.17
- Chemical Classification: Polyol sugar alcohol, pharmaceutical excipient, food sweetener, medical osmotic diuretic raw material
- Core Advantages
Natural hexitol derived from glucose hydrogenation. Low calorie, non-cariogenic sweetener, stable against acid and heat, no Maillard browning reaction. Excellent compressibility for tablet molding, good osmotic pressure regulation performance. Multiple grades: Pharma Grade, Food Grade, Cosmetic Grade, complying with USP/EP/FCC standards.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White crystalline powder or granular crystal
- Odor: Odorless, mild cool sweet taste
- Solubility: Slightly soluble in cold water, freely soluble in hot water; slightly soluble in ethanol; insoluble in ether and hydrocarbon solvents
- Melting Point: 166–169 °C
- Specific Optical Rotation [α]D20: +23° ~ +24° (10% aqueous solution)
- Hygroscopy: Non-hygroscopic under normal humidity environment
- Thermal characteristic: No caramelization when heated, stable in high-temperature processing
2.2 Chemical Properties
- Hexahydroxy polyol structure: Contains six hydroxyl groups, capable of esterification, etherification reaction
- Non-reducing sugar alcohol: No aldehyde group, does not react with Fehling reagent, resistant to discoloration under high temperature
- Acid & Alkali Stability: Stable in wide pH range (3–10), no degradation in weak acid/weak alkali formula
- Biochemical property: Hardly metabolized by oral bacteria, prevents dental caries; slowly absorbed by human intestine
- Photostability: No discoloration under long-term light exposure
- Compatibility: Compatible with most pharmaceutical raw materials, food additives and cosmetic actives
3. Main Application Fields
3.1 Pharmaceutical Industry (Core Usage)
- Osmotic diuretic injection raw material for lowering intracranial pressure and intraocular pressure;
- Tablet filler, binder and coating agent with superior moldability for oral solid preparations;
- Lyoprotectant for biological protein, vaccine and antibody freeze-dried formulations.
3.2 Food & Beverage Industry
Sugar-free sweetener for chewing gum, hard candy, baked goods and diabetic food; anti-caking agent and taste modifier.
3.3 Cosmetic Raw Material
Humectant and skin conditioner in facial cream, mask and oral care products, improves skin moisturizing feeling.
3.4 Chemical Synthetic Intermediate
Raw material for synthesizing mannitol hexanitrate and polyether/polyester polyol derivatives.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 69-65-8 |
| Molecular Formula | C6H14O6 |
| Molecular Weight | 182.17 |
| Appearance | White crystal powder |
| Assay | Pharma Grade ≥98.0%; Food Grade ≥99.0% |
| Water Content (KF) | ≤0.30% |
| Reducing Sugar | ≤0.05% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤3 ppm |
| Bulk Package | 25kg woven bag with PE inner liner |
| Sample Package | 1kg / 5kg sealed plastic bag |
| Storage Requirements | Hermetic dry warehouse ≤25℃; isolate humid environment and strong oxidants |
| Transportation Rule | Non-hazardous polyol raw material; moisture-proof packaging required during transit |
| Shelf Life | 36 months under intact sealed packaging |
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