Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: 2-nitrobenzaldehyde
- Aliases: o-Nitrobenzaldehyde, ONBA
- CAS Number: 552-89-6
- EINECS: 209-026-0
- Molecular Formula: C7H5NO3
- Molecular Weight: 151.12
- Chemical Classification: Nitro-substituted aromatic aldehyde intermediate, fine chemical synthetic raw material
- Core Advantages
Ortho-nitro substituted benzaldehyde with aldehyde and nitro groups on adjacent benzene ring carbons. Ortho steric and electronic effects bring unique reaction selectivity for cyclization, condensation and reduction reactions. Widely used for pharmaceutical intermediates, photosensitive materials, dye precursors and organic synthetic laboratory reagents.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: Pale yellow crystalline powder
- Odor: Slight aromatic aldehyde odor
- Solubility: Slightly soluble in water; soluble in ethanol, methanol, acetone, chloroform, toluene, ethyl acetate
- Melting Point: 42–44 °C
- Boiling Point: 156 °C (23 mmHg)
- Density: 1.284 g/cm3
- Hygroscopy: Non-hygroscopic under dry sealed storage
- UV feature: Obvious characteristic absorption peak in organic solvent
2.2 Chemical Properties
- Dual functional groups: Aromatic aldehyde (-CHO) + ortho nitro (-NO?); aldehyde undergoes Knoevenagel, aldol, Schiff base condensation; nitro group can be reduced to amino group
- Ortho substituent effect: Intramolecular hydrogen bonding exists between nitro oxygen and aldehyde hydrogen, improving molecular stability
- Reduction characteristic: Selective reduction of nitro to 2-aminobenzaldehyde, further cyclization to quinoline derivatives
- Acid & Alkali Stability: Stable under neutral and weak acidic conditions; undergoes aldol self-condensation under strong alkaline heating
- Thermal Stability: No decomposition below 100°C; slight sublimation under heating
- Photostability: Slightly discolor under long-term strong UV light
- Compatibility: Compatible with neutral aprotic solvents; incompatible with strong reducing agents, concentrated alkali, strong oxidants
3. Main Application Fields
3.1 Pharmaceutical Intermediate (Core Usage)
Key raw material for synthesizing quinoline, indole and heterocyclic drug skeletons; used for antibacterial, anti-inflammatory and cardiovascular drug intermediates via nitro reduction and cyclization.
3.2 Photosensitive & Photographic Materials
Precursor for preparing photochromic compounds, diazo photosensitive agents and photographic developer intermediates.
3.3 Dye & Pigment Intermediate
Building block for azo dyes, fluorescent dyes and organic pigment molecular structures.
3.4 Organic Synthetic Reagent
Standard aromatic ortho-nitro aldehyde reagent for Knoevenagel condensation, heterocyclic cyclization reaction research in chemical labs.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 552-89-6 |
| Molecular Formula | C7H5NO3 |
| Molecular Weight | 151.12 |
| Appearance | Pale yellow crystalline powder |
| GC Purity | Industrial Grade ≥98.0%; Synthetic Grade ≥99.0% |
| Moisture Content (KF) | ≤0.20% |
| Benzaldehyde Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Residue on Ignition | ≤0.05% |
| Bulk Package | 25kg PE lined fiber drum |
| Sample Package | 1kg / 5kg sealed plastic bucket |
| Storage Requirements | Hermetic cool dry warehouse ≤25℃; isolate strong light, reducing agents and alkaline raw materials |
| Transportation Rule | Common nitro aromatic intermediate; moisture-proof sealed packaging required during transit |
| Shelf Life | 24 months under intact sealed packaging |
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