Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Product Profile
- Full IUPAC Name: (2S)-2-amino-3-methylbutanoic acid
- Aliases: L-2-Amino-3-methylbutyric acid, L-Val
- CAS Number: 72-18-4
- EINECS: 200-773-6
- Molecular Formula: C5H11NO2
- Molecular Weight: 117.15
- Chemical Classification: Essential branched-chain amino acid (BCAA), nutritional fortifier, pharmaceutical raw material, culture medium reagent
- Core Advantages
Natural L-configured branched-chain essential amino acid, one of three BCAA series together with L-Leucine and L-Isoleucine. High biological utilization rate, participates in muscle energy metabolism and protein synthesis. Widely applied in sports nutrition supplements, compound amino acid injections, food additives, animal feed and biochemical research reagents. Stable crystalline structure, low hygroscopicity, good compatibility with other amino acids.
2. Physical & Chemical Properties
2.1 Physical Index
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Soluble in water; slightly soluble in ethanol; insoluble in acetone, ether, lipid solvents
- Melting Point: 313–314 °C (decomposes)
- Specific Optical Rotation [α]D20: +26.5° ~ +28.5° (c=8, 6mol/L HCl)
- pH (5% aqueous solution): 5.5–7.0 (near neutral)
- Hygroscopy: Slightly hygroscopic only under high humidity
2.2 Chemical Properties
- Dual functional groups: α-amino group and carboxyl group, typical amphoteric amino acid
- Amphoteric ion characteristic: Forms internal salt in aqueous solution; reacts with acid/alkali to generate stable salts
- Peptide synthesis: Amino group undergoes condensation with carboxylic acids to form peptide bonds for polypeptide & protein preparation
- Thermal Stability: Stable below 250°C; decomposes above melting point to release ammonia
- Acid & Alkali Stability: Stable in weak acid, neutral and mild alkaline environments; long-term high-temperature strong alkali triggers side chain degradation
- Photostability: No yellowing or impurity generation under normal light storage
- Compatibility: Compatible with all other amino acids, water-soluble nutritional raw materials; incompatible with strong oxidants, concentrated strong acid
3. Main Application Fields
3.1 Sports & Health Nutrition (Core Usage)
- BCAA compound supplement raw material: Relieves exercise fatigue, reduces muscle breakdown, accelerates post-workout recovery;
- Functional food fortifier for muscle support, weight management and elderly nutritional formulas.
3.2 Pharmaceutical Industry
- Raw material for compound amino acid infusions, oral amino acid preparations;
- Synthetic building block for targeted nutritional pharmaceuticals, postoperative recovery formulations.
3.3 Feed & Animal Nutrition
Feed additive for livestock, poultry and aquaculture; improves animal growth performance and meat quality.
3.4 Biochemical & Lab Reagent
Standard amino acid reference substance; additive for cell culture and microbial fermentation medium.
4. Quality Specification Table
| Test Item | Standard Index |
| CAS No. | 72-18-4 |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.15 |
| Appearance | White crystalline powder |
| HPLC Purity | Food Grade ≥98.5%; Pharma Grade ≥99.0%; Injection Grade ≥99.5% |
| Moisture Content (KF) | ≤0.30% |
| Specific Optical Rotation | +26.5° ~ +28.5° |
| Heavy Metals (Pb) | ≤10 ppm (Injection Grade ≤2 ppm) |
| Arsenic (As) | ≤2 ppm |
| Residue on Ignition | ≤0.10% |
| Bulk Package | 25kg PE lined fiber drum |
| Sample Package | 1kg / 5kg sealed moisture-proof plastic bucket |
| Storage Requirements | Hermetic cool dry warehouse ≤25℃; avoid humid air, strong oxidants and direct sunlight |
| Transportation Rule | Non-hazardous amino acid raw material; moisture-proof sealed packaging required during transit |
| Shelf Life | 36 months under intact sealed packaging |
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