1. Basic Info

2. Physical & Chemical Properties

Physical Properties

1. Appearance: White crystalline powder
2. Odor: Odorless
3. Solubility: Soluble in dichloromethane, tetrahydrofuran, dioxane, toluene; slightly soluble in hexane; insoluble in water
4. Melting Point: 137–140 °C
5. Density (25℃): 1.05 g/cm3
6. Boiling Point: Sublimes under vacuum at moderate temperature, decomposes at high pressure without boiling point
7. Flash Point: 110 °C
8. Hygroscopy: Slightly hygroscopic, sensitive to moisture and air
9. Storage requirement: Dry, inert gas sealed, low temperature storage recommended
10. Crystal feature: Regular crystal after recrystallization from hexane/toluene mixed solvent

Chemical Properties

1. Molecular structure: Two pinacol boronate rings connected by B-B single bond, stable neutral diboron reagent
2. B-B bond reactivity: Undergoes palladium-catalyzed borylation with aryl halides, alkenyl halides to generate aryl/alkenyl boronic esters
3. Hydrolysis stability: Stable in anhydrous neutral environment; slowly hydrolyzed in water/moisture to pinacol and boric acid
4. Thermal stability: Stable below 120 °C; above melting point slow sublimation, over 180 °C thermal decomposition
5. Acid-base stability: Decomposed rapidly by strong acid; stable under weak alkaline anhydrous conditions
6. Photostability: Avoid long-term UV irradiation; light accelerates minor decomposition
7. Compatibility: Compatible with anhydrous ether, halogenated aromatic solvents; incompatible with water, strong acid, protic solvents with high water content, strong oxidants

3. Main Application Fields

1. Aromatic borylation reagent (Core Application)

   Core borylation reagent for Miyaura borylation reaction. Reacts with aryl bromide, aryl iodide, aryl triflate under Pd catalysis to synthesize aryl boronic acid pinacol ester, key intermediate for Suzuki-Miyaura cross-coupling. Widely used in pharmaceutical intermediate and OLED material synthesis.
2. Suzuki coupling precursor raw material

   The prepared boronic esters are widely used for constructing C-C bonds in the synthesis of APIs, liquid crystal monomers, organic luminescent materials, pesticide intermediates, conjugated polymers.
3. Organic synthesis fine chemical building block

   Used for alkyne and alkene diboration reactions to generate vicinal diboron compounds, which can be further derivatized to diols, amino alcohols and other chiral functional molecules.
4. Pharmaceutical API synthetic intermediate

   Large-scale production of boronic acid-containing anti-cancer drugs, anti-inflammatory drugs, enzyme inhibitor raw materials; improves coupling yield and reduces side reactions compared with other boron reagents.
5. Organic electronic material raw material

   Synthesize aryl boronate monomers for OLED luminescent layers, organic field-effect semiconductors, conjugated polymer photoelectric materials.
6. Laboratory organic synthesis standard reagent

   Universal borylation reagent for organic methodology research, catalyst screening and new coupling reaction development.

4. Quality Specification Table