Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: Oxfendazole
Alias: Methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate
CAS No.: 53716-50-0
Molecular Formula: C15H13N3O3S
Molecular Weight: 315.35
2. Physical & Chemical Properties
Physical Properties
- Appearance: White to pale beige crystalline powder, odorless
- Solubility: Practically insoluble in water; slightly soluble in methanol, ethanol; soluble in DMSO, chloroform
- Melting Point: 252–254 ℃ (decompose upon melting)
- UV characteristic: Characteristic absorption peak at 298 nm in methanol
- Hygroscopy: Non-hygroscopic under normal ambient humidity
- Crystal form: Fine needle crystal recrystallized from methanol
Chemical Properties
- Molecular structure: Benzimidazole veterinary anthelmintic, containing carbamate group and phenyl sulfinyl group
- Weak acidity: N-H on benzimidazole ring, can react with strong alkali to form soluble salts
- Oxidation susceptibility: Sulfinyl group easy to oxidize into sulfone by oxidants, reduce drug efficacy
- Photostability: Sensitive to strong UV light, long-term illumination generates oxidation impurities
- Thermal stability: Stable below 180 ℃; carbonize and decompose above melting point
- Acid-base stability: Stable in neutral and weak acid environment; concentrated strong acid hydrolyzes carbamate side chain
- Compatibility: Compatible with common veterinary auxiliary materials; incompatible with strong oxidants, concentrated acid/alkali
3. Main Application Fields
1. Veterinary Anthelmintic API (Core Application)
- Broad-spectrum deworming raw material for cattle, sheep, pigs, horses, dogs
- Effective against gastrointestinal nematodes, lungworms, tapeworms, inhibits parasite tubulin synthesis to kill worms
- Made into oral suspension, bolus, premix for livestock breeding
2. Animal Husbandry Premix Raw Material
Compound feed additive for prevention and control of parasitic diseases in ruminants
3. Pharmaceutical Quality Control Standard
HPLC reference standard for oxfendazole raw material and veterinary finished drug detection
4. Pharmacological Laboratory Research Reagent
Positive control reagent for anti-parasite in vitro and in vivo pharmacodynamic experiments
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 53716-50-0 |
| Molecular Formula | C15H13N3O3S |
| Molecular Weight | 315.35 |
| Appearance | White pale beige crystal powder |
| HPLC Purity | Veterinary Grade ≥98.0%; Reference Standard ≥99.5% |
| Single Maximum Impurity | ≤0.5% |
| Total Related Substances | ≤1.5% |
| Moisture Content (KF) | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Bulk Package | Light-proof aluminum foil vacuum bag, amber sealed glass bottle |
| Storage Condition | Hermetic light-proof cool dry warehouse ≤25℃; avoid high temperature and sunlight |
| Transportation Rule | Veterinary drug raw material, sealed light-proof moisture-proof packaging |
| Shelf Life | 24 months under intact vacuum packaging |
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