Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: Retinyl acetate
Alias: Vitamin A acetate, all-trans-retinol acetate
CAS No.: 127-47-9
Molecular Formula: C22H32O2
Molecular Weight: 328.49
2. Physical & Chemical Properties
Physical Properties
- Appearance: Pale yellow crystalline solid; oily liquid after melting
- Odor: Faint characteristic fishy fat odor
- Solubility: Insoluble in water; soluble in ethanol, chloroform, acetone, vegetable oils, ether
- Melting Point: 57–58 ℃
- UV-Vis feature: Maximum absorption at 326 nm in ethanol solvent
- Hygroscopy: Non-hygroscopic
- Crystal form: Flaky crystal recrystallized from n-hexane
Chemical Properties
- Molecular structure: All-trans polyene retinoid, hydroxyl group of retinol esterified with acetic acid, long conjugated polyene chain
- Oxidation susceptibility: Conjugated double bonds easily oxidized by oxygen, heat and light, color fades and activity declines
- Photodegradation: Extremely sensitive to UV and strong light, isomerizes into cis-isomers with reduced physiological activity
- Saponification: Under alkaline heating hydrolysis to retinol and acetate ion
- Thermal stability: Stable below 60 ℃; high temperature above 100 ℃ accelerates oxidative decomposition
- Antioxidant matching: Compound with vitamin E can effectively slow down oxidation deterioration
- Compatibility: Compatible with plant oils, fat-soluble excipients; incompatible with heavy metal ions, strong oxidants, concentrated acid
3. Main Application Fields
1. Food & Feed Nutrition Fortifier (Core Application)
- Vitamin A nutritional supplement for dairy, beverage, candy, infant formula
- Feed additive for poultry, livestock, aquatic animals to maintain vision and epithelial tissue health
- Microcapsule retinyl acetate for water-soluble food fortification system
2. Cosmetic Active Raw Material
- Anti-aging anti-wrinkle ingredient for cream, essence, mask, eye cream
- Promote keratin metabolism, improve rough skin, fade fine lines and hyperpigmentation
3. Pharmaceutical API & Excipient
- Raw material for vitamin A oral soft capsules, drops for treating vitamin A deficiency
- Auxiliary for ophthalmic ointment to repair corneal epithelial damage
4. Biochemical Standard Reference
HPLC standard substance for vitamin A content detection in food, feed and pharmaceutical preparations
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 127-47-9 |
| Molecular Formula | C22H32O2 |
| Molecular Weight | 328.49 |
| Appearance | Pale yellow crystal solid |
| HPLC Purity | Food/Feed Grade ≥98.0%; Pharma Grade ≥99.0% |
| All-trans Content | ≥92% |
| Moisture Content (KF) | ≤0.10% |
| Residue on Ignition | ≤0.05% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Bulk Package | Nitrogen-filled light-proof aluminum foil vacuum bag, amber sealed glass bottle |
| Storage Condition | Hermetic nitrogen-sealed, light-proof, low temperature ≤20℃ warehouse; avoid air contact and sunlight |
| Transportation Rule | Light-sensitive fat-soluble vitamin solid, cold insulated sealed packaging |
| Shelf Life | 24 months under intact nitrogen vacuum packaging |
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