Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Info
Name: 4'-Methylpropiophenone
Alias: 4-Methylpropiophenone, p-Methylpropiophenone
CAS No.: 5337-93-9
Molecular Formula: C10H12O
Molecular Weight: 148.20
2. Physical & Chemical Properties
Physical Properties
- Appearance: Colorless to pale yellow transparent oily liquid
- Odor: Mild aromatic ketone odor
- Solubility: Insoluble in water; miscible with ethanol, methanol, acetone, toluene, ethyl acetate, dichloromethane
- Melting Point: 6–8 ℃
- Boiling Point: 238–241 ℃
- Density (20℃): 0.992–0.996 g/cm3
- Refractive Index nD20: 1.528–1.531
- Flash Point: >100 ℃
- Hygroscopy: Non-hygroscopic
- Volatility: Low volatility at room temperature
Chemical Properties
- Molecular structure: Aromatic ketone, methyl group at para-position of benzene ring, propanoyl side chain
- Carbonyl characteristic: Undergoes aldol condensation, reductive amination, reduction to alcohol/alkane
- Aromatic substitution: Benzene ring can conduct halogenation, nitration under acid catalysis
- Oxidation: Side chain methyl easily oxidized to carboxyl group by strong oxidants
- Thermal stability: Stable below 200 ℃; high temperature above 260 ℃ cracking occurs
- Photostability: Long-term strong light exposure turns yellow slightly
- Compatibility: Compatible with common organic solvents; avoid mixing with strong oxidants, concentrated strong alkali
3. Main Application Fields
1. Pharmaceutical Synthetic Intermediate (Core Application)
- Key raw material for synthesis of anti-inflammatory, psychotropic, cardiovascular drug intermediates
- Precursor for chiral amine, heterocyclic fine chemical preparation
2. Fragrance & Flavor Intermediate
Synthetic raw material for floral, woody spice monomers
3. Organic Synthesis Laboratory Reagent
Raw material for carbonyl compound derivatization, asymmetric synthesis research
4. Coating & Ink Auxiliary High-boiling Solvent
Slow-drying solvent to improve coating leveling and gloss
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 5337-93-9 |
| Molecular Formula | C10H12O |
| Molecular Weight | 148.20 |
| Appearance | Colorless light yellow clear liquid |
| GC Purity | Synthetic Grade ≥99.0%; High Purity Grade ≥99.5% |
| Moisture Content | ≤0.10% |
| Acid Value | ≤0.1 mgKOH/g |
| Color (APHA) | ≤20 |
| Heavy Metals (Pb) | ≤10 ppm |
| Bulk Package | 200L plastic-lined iron drum / 25kg plastic barrel |
| Storage Condition | Hermetic cool dry warehouse ≤25℃; isolate sunlight and oxidants |
| Transportation Rule | Aromatic ketone liquid, sealed anti-leakage fireproof packaging |
| Shelf Life | 24 months under intact sealed packaging |
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