Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Analgin
Alias: Metamizole sodium, Sodium dipyrone
CAS No.: 5907-38-0
Molecular Formula: C13H16N3NaO4S
Molecular Weight: 333.34
2. Physical and Chemical Properties
Physical Properties
- Appearance: White or slightly yellow crystalline powder
- Odor: Slightly characteristic odor, slightly bitter taste
- Solubility: Freely soluble in water; soluble in methanol and ethanol; insoluble in ether, benzene and chloroform
- Melting Point: Decomposes above 120 °C
- Hygroscopicity: Strongly hygroscopic, readily absorbs moisture in humid air
- Aqueous solution property: Aqueous solution shows weak alkalinity, turns pale yellow upon long-term storage
Chemical Properties
- Molecular structure: Pyrazolone non-steroidal anti-inflammatory sodium salt, contains sulfonate functional group
- Hydrolysis: Gradually hydrolyzes in aqueous solution to generate 4-aminoantipyrine and formaldehyde; accelerated under heating or acidic conditions
- Oxidation: Easily oxidized by air and light, discoloration from white to yellow and brown
- Thermal stability: Unstable at high temperature, decomposes to release irritant gas
- Pharmacological activity: Analgesic, antipyretic and anti-inflammatory effects by inhibiting prostaglandin synthesis
- Compatibility: Compatible with neutral polar solvents; incompatible with strong oxidants, acidic substances and heavy metal salts
3. Main Application Fields
1. Pharmaceutical Active Pharmaceutical Ingredient (Core Application)
- Clinical antipyretic and analgesic drug for fever, headache, neuralgia, joint pain and dysmenorrhea
- Raw material for injection, oral tablets and oral solution formulations
2. Veterinary Medicine Raw Material
Antipyretic analgesic for livestock and poultry to relieve fever and somatic pain
3. Forensic Toxicology Reference Standard
Calibration standard for HPLC/LC-MS detection of pyrazolone analgesic residues
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 5907-38-0 |
| Molecular Formula | C13H16N3NaO4S |
| Molecular Weight | 333.34 |
| Appearance | White to pale yellow crystalline powder |
| HPLC Purity | Pharma Grade ≥99.0% |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | Qualified as standard specification |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | 25kg fiber drum lined with PE film, nitrogen-filled amber vacuum bag |
| Storage Condition | Hermetic, light-proof and dry warehouse below 25 °C; strictly isolate moisture and sunlight |
| Transportation Requirement | API solid with strong hygroscopy, sealed moisture-proof and light-proof packaging |
| Shelf Life | 24 months under intact nitrogen-filled light-proof packaging |
...
Product
