Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Allantoin
Alias: 5-Ureidohydantoin
CAS No.: 97-59-6
Molecular Formula: C4H6N4O3
Molecular Weight: 158.12
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless, tasteless
- Solubility: Slightly soluble in cold water, soluble in hot water and dilute alkaline solution; slightly soluble in ethanol; insoluble in chloroform, ether and mineral oil
- Melting Point: 230–234 °C (decomposes)
- Aqueous solution pH: Neutral to weak acid
- Hygroscopicity: Slightly hygroscopic under high humidity
- Crystal morphology: Fine flaky crystals recrystallized from hot water
Chemical Properties
- Molecular structure: Heterocyclic urea derivative, contains multiple amide and imide functional groups
- Hydrolysis property: Slowly hydrolyzes under strong acid or high temperature to generate urea and glyoxylic acid
- Complexation ability: Can form stable complexes with metal ions, relieve skin irritation caused by heavy metals
- Thermal stability: Stable below 180 °C; decomposition occurs above melting point to release ammonia
- Photostability: Stable under normal light, no obvious discoloration after long-term sealed storage
- Compatibility: Compatible with most cosmetic, pharmaceutical and daily chemical raw materials; incompatible with strong alkali, concentrated oxidants and high-concentration strong acid
3. Main Application Fields
1. Cosmetic Active Ingredient (Core Application)
- Skin repairing additive for facial cream, mask, toner and after-sun products; accelerates epidermal cell regeneration, soothes red and sensitive skin
- Anti-dandruff, hair follicle repairing raw material in shampoo and hair conditioner
- Keratolytic and moisturizing ingredient for hand care, foot care and exfoliating products
2. Pharmaceutical Excipient & API Intermediate
- External ointment raw material for treating minor wounds, burns, chapped skin and mild dermatitis
- Stabilizer and soothing agent for oral external lotion and dermatological preparations
3. Daily Chemical & Oral Care Raw Material
Soothing additive for toothpaste, mouthwash to relieve oral mucosal irritation and reduce gum inflammation
4. Biochemical Research Reagent
Standard substrate for urea cycle related enzyme activity research
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 97-59-6 |
| Molecular Formula | C4H6N4O3 |
| Molecular Weight | 158.12 |
| Appearance | White crystalline powder |
| HPLC Purity | Cosmetic/Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Water Content (KF) | ≤0.30% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | Nitrogen-filled aluminum foil vacuum bag / 25kg PE-lined fiber drum |
| Storage Condition | Hermetic dry warehouse below 25 °C; avoid high temperature and strong alkaline environment |
| Transportation Requirement | Skin care repair raw material solid, dust-proof moisture-proof sealed packaging |
| Shelf Life | 36 months under intact sealed packaging |
Safety Warning
Low irritation and high safety for human skin. Dust may cause mild discomfort to respiratory tract and eyes during operation; wear dust mask and protective gloves in ventilated environment. Avoid long-term mixing with strong alkaline substances to prevent hydrolysis and efficacy decline.
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