Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Chlorhexidine Digluconate
Alias: 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] digluconate
CAS No.: 18472-51-0
Molecular Formula: C22H30Cl2N10·2C6H12O7
Molecular Weight: 897.76
2. Physical and Chemical Properties
Physical Properties
- Appearance: Colorless to pale yellow transparent viscous liquid (commonly supplied as 20% aqueous solution)
- Odor: Slight characteristic odor
- Solubility: Miscible freely with water, ethanol, propylene glycol; insoluble in non-polar solvents such as mineral oil, chloroform
- Aqueous solution pH: 5.5–7.0
- Hygroscopicity: Liquid product has high water miscibility, no obvious hygroscopicity
- Surface activity: Cationic surfactant, adsorbs to bacterial cell membrane surface
Chemical Properties
- Molecular structure: Cationic biguanide compound complexed with two gluconate anions
- Broad-spectrum bactericidal mechanism: Positively charged molecules combine with negatively charged bacterial proteins, denature cytoplasm and kill bacteria, fungi and partial viruses
- Ion incompatibility: Precipitates immediately when mixed with anionic surfactants, soap, phosphate and carbonate
- Thermal stability: Stable under normal temperature; long-term boiling will reduce effective bactericidal content
- Photostability: Stable under indoor light; avoid long-term strong ultraviolet irradiation
- Compatibility: Compatible with nonionic surfactants, neutral thickeners; incompatible with anionic raw materials, heavy metal salts, iodine preparations
3. Main Application Fields
1. Medical Disinfectant Raw Material (Core Application)
- Skin preoperative disinfection, wound cleaning, oral mucosal disinfection, gynecological lavage disinfection
- Raw material for antibacterial mouthwash, surgical hand sanitizer, burn care disinfectant
- Long-acting bacteriostatic agent for medical catheters and wound dressings
2. Daily Oral Care Raw Material
Antibacterial additive for toothpaste, mouthwash to inhibit dental plaque, relieve gingivitis and halitosis
3. Cosmetic & Personal Care Preservative
Low-irritation bacteriostatic ingredient for facial cleanser, body wash, facial mask and feminine care lotion
4. Industrial Sanitary Disinfectant
Bactericide for public facility surface disinfection, textile antibacterial finishing agent
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 18472-51-0 |
| Molecular Formula | C22H30Cl2N10·2C6H12O7 |
| Molecular Weight | 897.76 |
| Appearance | Pale yellow viscous liquid |
| Active Content | 19.0%–21.0% (aqueous solution) |
| pH Value | 5.5–7.0 |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | 25L PE plastic drum sealed packaging |
| Storage Condition | Hermetic cool warehouse below 25 °C; isolate anionic substances and iodine disinfectants |
| Transportation Requirement | Antibacterial liquid raw material, sealed leak-proof packaging |
| Shelf Life | 24 months under intact sealed packaging |
Safety Warning
Irritating to eyes and mucous membranes; high concentration may cause skin dryness. Strictly avoid mixing with soap, anionic detergents and povidone iodine to prevent precipitation and loss of efficacy. Operations shall be carried out in ventilated space with chemical-resistant gloves and goggles. Do not swallow.
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