Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Poly(ethylene glycol)
Abbreviation: PEG
Alias: Polyoxyethylene, Macrogol, Polyethylene oxide (low molecular weight)
CAS No.: 25322-68-3
General Molecular Formula: H1O1-(C2H4O1)n-H1
Molecular Weight Series: PEG 200, 400, 600, 1000, 4000, 6000, 8000, 10000 etc.
2. Physical and Chemical Properties
Physical Properties
- Low molecular weight (PEG 200–600): Colorless transparent viscous liquid
- Medium & high molecular weight (PEG 1000 and above): White waxy solid / crystalline powder
- Odor: Odorless, slight faint sweet taste
- Solubility: Miscible freely with water, methanol, ethanol, acetone; partially soluble in dichloromethane; insoluble in aliphatic hydrocarbons, mineral oil, vegetable oil
- Melting Point: Rises with molecular weight; PEG400 ~4–8 °C, PEG1000 ~37–40 °C, PEG6000 ~58–63 °C
- Density: 1.12–1.13 g/cm3 (20 °C)
- Hygroscopicity: Strongly hygroscopic; lower molecular weight PEG absorbs more moisture
Chemical Properties
- Molecular Structure: Linear polyether terminated with two H1O1 groups, repeating C2H4O1 ether units
- Hydroxyl reactivity: Terminal -O1H1 can undergo esterification, etherification, cross-linking to produce PEG derivatives (PEG ester, PEG amine, PEG aldehyde)
- Thermal stability: Stable below 120 °C; above 180 °C thermal oxidation, chain cleavage generates aldehyde and acidic impurities
- Photostability: Stable under indoor light; long-term UV irradiation accelerates oxidative degradation
- pH stability: Stable in neutral / weak acid / weak alkaline environment; easy to degrade under strong alkali high temperature
- Compatibility: Compatible with most polar raw materials, resins, surfactants, pharmaceutical excipients; incompatible with tannins, phenols, iodine, strong oxidants
3. Main Application Fields
1. Pharmaceutical Excipients (Core Application)
- Solvent & co-solvent for injections, oral liquids, ointments, suppositories
- Lubricant, binder and film-coating agent for tablets; solubilizer for poorly soluble APIs
- PEGylation carrier for protein / polypeptide long-acting drugs to extend half-life
2. Cosmetic & Personal Care Raw Material
- Humectant, thickener, solubilizer for toner, cream, mask, shampoo
- Lubricating agent for skincare and hair care formulations, improves spreading property
3. Food & Food Additive
- Antifoaming agent, coating agent, carrier for food flavors and food colorants
- Lubricant for food anti-caking and candy demolding
4. Industrial Chemicals
- Water-soluble lubricant, metal cutting fluid additive, textile softener
- Dispersant for ceramic, printing ink, water-based coating; binder for battery materials
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 25322-68-3 |
| General Formula | H1O1-(C2H4O1)n-H1 |
| Appearance | Liquid / white waxy solid (depends on molecular weight) |
| Hydroxyl Value | Matches specified molecular weight grade |
| Water Content (KF) | ≤0.20% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | 200L plastic drum (liquid PEG) / 25kg PE lined fiber drum (solid PEG) |
| Storage Condition | Hermetic cool dry warehouse below 25 °C; isolate strong oxidants |
| Transportation Requirement | Non-dangerous goods, moisture-proof sealed packaging |
| Shelf Life | 36 months under intact sealed packaging |
Safety Warning
Low toxicity, approved safe excipient for food, medicine and cosmetics within normal dosage. High-concentration dust of solid PEG may mildly irritate respiratory tract and eyes; wear dust mask and gloves during handling. Avoid long-term heating above 180 °C to prevent oxidative decomposition and irritant volatile substances. Seal storage to prevent moisture absorption.
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