Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Adenosine
Alias: 9-β-D-Ribofuranosyladenine
CAS No.: 58-61-7
Molecular Formula: C10H13N5O4
Letter-number format molecular formula: C10H13N5O4
Molecular Weight: 267.24
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Slightly soluble in cold water, soluble in hot water; slightly soluble in methanol; insoluble in ethanol, acetone, ether and lipid solvents
- Melting Point: Decomposes at 234–236 °C
- Hygroscopicity: Slightly hygroscopic under high humidity conditions
- Crystal property: Needle crystal obtained by recrystallization from hot water
Chemical Properties
- Molecular Structure: Nucleoside compound composed of adenine purine base and ribose pentose linked by β-N-glycosidic bond, contains amino and multiple hydroxyl functional groups
- Glycosidic bond characteristic: Stable under neutral and weak acid environment; glycosidic bond hydrolyzes under strong acid heating to generate adenine and ribose
- Hydroxyl reactivity: Multiple ribose hydroxyl groups can undergo esterification, phosphorylation to produce ATP, ADP, AMP nucleotide derivatives
- Thermal stability: Stable below 180 °C; high temperature triggers carbonization and decomposition
- Photostability: Slightly sensitive to intense ultraviolet light; aqueous solution gradually discolors under long-term light irradiation
- Compatibility: Compatible with neutral aqueous pharmaceutical excipients; incompatible with strong mineral acids, strong oxidants and heavy metal salts
3. Main Application Fields
1. Pharmaceutical API & Nucleoside Intermediate (Core Application)
- Raw material for antiarrhythmic injection preparations, clinically used for paroxysmal supraventricular tachycardia treatment
- Key synthetic precursor for adenosine triphosphate (ATP), adenosine monophosphate (AMP) and antiviral nucleoside drugs
2. Biochemical & Laboratory Reagent
- Standard substrate for enzymology, cell metabolism and cardiovascular mechanism research
- HPLC reference standard for nucleoside residue testing in biological samples and pharmaceutical products
3. Health Care Raw Material
Functional additive for nutritional supplements to improve myocardial energy metabolism and relieve fatigue
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 58-61-7 |
| Molecular Formula | C10H13N5O4 |
| Appearance | White crystalline powder |
| HPLC Assay | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Melting Point (Decompose) | 234–236 °C |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | Nitrogen-filled amber aluminum foil vacuum bag / 25kg PE-lined fiber drum |
| Storage Condition | Hermetic cool dark warehouse below 25 °C; segregated from acidic and oxidizing substances |
| Transportation Requirement | Nucleoside pharmaceutical solid, dust-proof light-proof sealed packaging |
| Shelf Life | 36 months under intact nitrogen-sealed vacuum packaging |
Safety Warning
Low acute toxicity nucleoside compound. Dust inhalation irritates nasal mucosa and eyes; wear dust mask and chemical-resistant gloves during operation. Avoid long-term storage under strong light and high temperature to prevent hydrolysis impurities. Waste residues and waste liquid belong to pharmaceutical organic hazardous waste and need professional centralized harmless disposal.
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