Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Sodium hyaluronate
Alias: Sodium hyaluronan, HA sodium salt
CAS No.: 9067-32-7
Repeating unit molecular formula: C14H20N1O11Na1
Molecular weight: Variable, ranging from thousands to millions, determined by molecular weight grade
2. Physical and Chemical Properties
Physical Properties
- Appearance: White fibrous powder or fine powder
- Odor: Odorless
- Solubility: Fully soluble in water to form highly viscous transparent gel; insoluble in ethanol, acetone, ether and other organic solvents
- Hygroscopicity: Extremely strong hygroscopicity, quickly absorbs moisture in air to agglomerate
- Aqueous property: Neutral weak viscous aqueous solution, good lubricity and film-forming property
- Viscosity characteristic: Viscosity drops sharply under high temperature, strong acid, strong alkali and high shear force
Chemical Properties
- Molecular structure: Linear polysaccharide sodium salt polymer, alternately composed of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide repeating units
- Acid-base stability: Stable under neutral and weak acid conditions; glycosidic bond hydrolyzes under strong acid/strong alkali heating to reduce molecular weight
- Enzymatic degradation: Hyaluronidase can break molecular chain and degrade viscosity
- Thermal stability: Stable below 40°C; long-term heating above 80°C causes molecular chain breakage and viscosity decline
- Photostability: Sensitive to ultraviolet light; long-term light irradiation accelerates degradation and discoloration
- Compatibility: Compatible with most cosmetic, food and pharmaceutical water-soluble raw materials; incompatible with high-concentration alcohol, strong oxidants, heavy metal ions
3. Main Application Fields
1. Cosmetic Raw Material (Core Application)
- High-efficiency humectant for essence, facial cream, mask, eye care products, forms water-locking protective film on skin surface
- Lubricating repair additive for shampoo and body wash to smooth hair and relieve dry skin
2. Medical & Pharmaceutical Excipient
- Intra-articular injection raw material for joint lubrication to relieve osteoarthritis pain
- Ophthalmic viscoelastic agent for cataract surgery; raw material for eye drops to relieve dry eyes
- Wound repair gel raw material to promote skin tissue healing
3. Food & Health Care Raw Material
Oral health food additive, intestinal moisturizing, skin care functional ingredient
4. Biochemical Research Reagent
Cell culture medium additive, tissue engineering scaffold raw material
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 9067-32-7 |
| Repeating Unit Formula | C14H20N1O11Na1 |
| Appearance | White fibrous powder |
| Molecular Weight | Low/Medium/High molecular weight customizable |
| Water Content (KF) | ≤10.0% |
| Protein Impurity | Cosmetic grade ≤0.1%; injection grade ≤0.05% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤1 ppm |
| Packaging | Nitrogen-filled aluminum foil vacuum bag / 25kg PE lined fiber drum |
| Storage Condition | Hermetic cool dark dry warehouse below 25°C; strictly moisture-proof and light-proof |
| Transportation Requirement | Hygroscopic biological polysaccharide solid, fully sealed packaging |
| Shelf Life | 24 months under intact nitrogen-sealed vacuum packaging |
Safety Warning
Low-toxicity biological macromolecule raw material. Dust inhalation irritates nasal mucosa and eyes; avoid direct inhalation of fine powder. Wear dust mask and chemical-resistant gloves during operation. Must be completely sealed to prevent deliquescence and molecular weight degradation. Avoid long-term high temperature and light exposure. Waste can be treated as general biodegradable organic waste.
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