Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
1. Basic Information
Name: Testosterone propionate
Alias: 17β-Hydroxyandrost-4-en-3-one propionate
CAS No.: 57-85-2
Molecular Formula: C22H32O3
Letter-number format molecular formula: C22H32O3
Molecular Weight: 344.49
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Insoluble in water; soluble in ethanol, chloroform, acetone, ether, vegetable oil; slightly soluble in methanol
- Melting Point: 118–123 °C
- Hygroscopicity: Non-hygroscopic under normal ambient humidity
- Optical characteristic: Optically active chiral steroid compound
Chemical Properties
- Molecular Structure: Short-chain esterified androgen steroid, androstane four-ring skeleton, C4-C5 double bond, 3-ketone group, 17-position propionate ester group
- Ester hydrolysis characteristic: Stable under neutral and weak acid environment; ester bond hydrolyzes under strong acid/alkali heating to generate free testosterone
- Functional group reactivity: Conjugated ketone can undergo reduction, addition, oximation reactions
- Thermal stability: Stable below 100 °C; thermal decomposition above 220 °C to produce steroid degradation impurities
- Photostability: Sensitive to ultraviolet light; long-term light irradiation turns yellow and produces oxidation impurities
- Compatibility: Compatible with oily pharmaceutical excipients; incompatible with strong oxidants, concentrated mineral acids, heavy metal ions
3. Main Application Fields
1. Pharmaceutical API (Core Application)
- Injectable androgen raw material, clinically used for male testosterone deficiency, hypogonadism, male infertility
- Key steroid intermediate for synthesizing other androgen, anti-estrogen and contraceptive hormone drugs
2. Biochemical Laboratory Reagent
HPLC reference standard for androgen detection; tool compound for endocrinology and reproductive cell research
3. Fine Chemical Synthetic Intermediate
Precursor for preparing long-acting testosterone ester derivatives
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 57-85-2 |
| Molecular Formula | C22H32O3 |
| Appearance | White crystalline powder |
| HPLC Assay | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Melting Point | 118–123 °C |
| Water Content (KF) | ≤0.30% |
| Residue on Ignition | ≤0.10% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Packaging | Nitrogen-filled amber aluminum foil vacuum bag / 25kg PE-lined fiber drum |
| Storage Condition | Hermetic cool dark warehouse below 25 °C; strictly isolated from light, oxidants and acidic substances |
| Transportation Requirement | Controlled steroid hormone solid, dust-proof light-proof fully sealed packaging |
| Shelf Life | 36 months under intact nitrogen-sealed vacuum packaging |
Safety Warning
Endocrine active controlled steroid substance. Dust inhalation irritates eyes, nasal mucosa and respiratory tract; long-term skin contact interferes human hormone balance, abnormal hormone levels may cause organ damage. Pregnant women, adolescents, children are prohibited from any direct contact. Wear dust mask, chemical-resistant gloves and full-face protective goggles during all operations, operate in fully ventilated workshop. Avoid light and high temperature during storage to prevent oxidative degradation. Waste residues and waste liquid are pharmaceutical hazardous waste and must be professionally recycled and disposed in accordance with hormone chemical waste regulations.
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