Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Glutathione
1. Basic Information
Name: Glutathione
Alias: γ-L-Glutamyl-L-cysteinylglycine, GSH
CAS No.: 70-18-8
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.33
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless, slight sour taste
- Solubility: Freely soluble in H2O; slightly soluble in CH3OH; insoluble in C2H5OH, acetone and lipid solvents
- Melting Point: Decomposes above 190 °C without clear melting point
- Hygroscopicity: Moderately hygroscopic under high humidity
- Aqueous Characteristic: Weakly acidic aqueous solution with strong reducing property
Chemical Properties
- Molecular Structure: Tripeptide composed of glutamic acid, cysteine and glycine, containing active sulfhydryl group (-SH)
- Reducing Activity: The sulfhydryl group easily oxidizes under air and UV light to form oxidized glutathione (GSSG)
- Acid-base Stability: Stable under weak acidic environment; rapidly hydrolyzed under strong acid or alkaline heating
- Thermal Stability: Stable below 40 °C; high temperature accelerates oxidation and peptide bond cleavage
- Photostability: Highly sensitive to ultraviolet light; long-term illumination loses activity and turns yellow
- Compatibility: Incompatible with strong oxidants, heavy metal ions and alkaline substances
3. Main Application Fields
1. Health Food & Nutraceutical Raw Material (Core Application)
- Antioxidant supplement for anti-aging, liver protection and immunity improvement
- Skin brightening functional additive for oral beauty products
2. Cosmetic Active Ingredient
Skin whitening, antioxidant raw material for serum, facial mask and cream to inhibit melanin formation
3. Pharmaceutical Excipient & API Intermediate
Liver-protecting injection raw material; stabilizer for biological preparations
4. Biochemical Research Reagent
Reducing agent for cell culture, enzyme activity test and protein analysis
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 70-18-8 |
| Molecular Formula | C10H17N3O6S |
| Appearance | White crystalline powder |
| HPLC Purity | Food Grade ≥98.0%; Pharma Grade ≥99.0% |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Oxidized Glutathione (GSSG) | ≤1.0% |
| Heavy Metals (Pb1) | ≤10 ppm |
| Packaging | Nitrogen-purged amber aluminum foil vacuum bag / 25kg PE lined fiber drum |
| Storage Condition | Hermetically sealed in cool dark warehouse below 25 °C; strictly moisture-proof, light-proof and isolated from oxidants |
| Transportation Requirement | Oxidation-prone bioactive peptide, light-proof fully sealed packaging |
| Shelf Life | 24 months under nitrogen-sealed vacuum packaging |
Safety Warning
Low-toxic biological peptide powder. Dust irritates eyes and respiratory tract. Wear dust mask, chemical-resistant gloves and protective goggles during operation with ventilation. Keep sealed to avoid air oxidation deactivation. Waste liquid needs neutralization treatment before discharge; solid waste can be treated as biodegradable organic waste.
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