Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Testosterone Cypionate
1. Basic Information
Name: Testosterone Cypionate
Alias: 17β-Hydroxyandrost-4-en-3-one cyclopentylpropionate
CAS No.: 58-20-8
Molecular Formula: C27H40O3
Molecular Weight: 412.60
2. Physical and Chemical Properties
Physical Properties
- Appearance: White to off-white crystalline powder
- Odor: Odorless steroid solid
- Solubility: Insoluble in H2O; freely soluble in CHCl3, ether, vegetable oil; soluble in CH3OH and C2H5OH
- Melting Point: 98–104 °C
- Hygroscopicity: Non-hygroscopic under normal ambient humidity
- Aqueous Characteristic: Hydrophobic, neutral oily soluble steroid compound
Chemical Properties
- Molecular Structure: Long-acting ester androgen steroid with androstane four-ring skeleton, C4-C5 conjugated ketone group, 17-position cyclopentylpropionate ester group
- Ester Hydrolysis Feature: Stable under neutral and weak acidic environment; ester bond hydrolyzes under strong acid or alkaline heating to release free testosterone
- Oxidation Property: Prone to oxidative yellowing under long-term UV light and air exposure
- Thermal Stability: Stable below 80 °C; thermal decomposition occurs at high temperature above melting point
- Photostability: Sensitive to ultraviolet radiation; light irradiation generates oxidative impurities
- Compatibility: Compatible with oily excipients for injection formulation; incompatible with strong oxidants, concentrated alkali and heavy metal ions
3. Main Application Fields
1. Pharmaceutical Active Pharmaceutical Ingredient (Core Application)
Long-acting injectable androgen raw material, clinically applied for male hypogonadism, testosterone deficiency, male infertility and breast cancer palliative treatment
2. Endocrinology Research Reagent
Reference standard for androgen detection; tool compound for reproductive cell and animal model experiments
3. Steroid Synthetic Intermediate
Precursor for manufacturing other androgen and anti-androgen pharmaceutical derivatives
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 58-20-8 |
| Molecular Formula | C27H40O3 |
| Appearance | White crystalline powder |
| HPLC Purity | Pharma Grade ≥99.0%; Reference Standard ≥99.5% |
| Water Content (KF) | ≤0.30% |
| Melting Range | 98–104 °C |
| Residue on Ignition | ≤0.10% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb1) | ≤10 ppm |
| Packaging | Nitrogen-purged amber aluminum foil vacuum bag / 25kg PE-lined fiber drum |
| Storage Condition | Hermetically sealed in cool dark warehouse below 25 °C; strictly isolated from light, air oxidants and alkaline chemicals |
| Transportation Requirement | Controlled endocrine steroid solid, light-proof fully sealed packaging |
| Shelf Life | 36 months under nitrogen-sealed vacuum packaging |
Safety Warning
Endocrine-active controlled steroid substance. Dust severely irritates eyes, respiratory tract and skin; inhalation or percutaneous absorption disrupts human hormone balance, leading to organ dysfunction. Operate in fully ventilated fume hood with dust mask, chemical-resistant gloves and full-face sealed goggles. Keep airtight storage to avoid photooxidation degradation. Waste liquid needs solvent recovery and detoxification treatment; solid waste is classified as hazardous pharmaceutical waste and must be disposed by professional hazardous waste institutions.
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