Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Rutin
1. Basic Information
Name: Rutin
Alias: Rutoside, Quercetin-3-O-rutinoside
CAS No.: 153-18-4
Molecular Formula: C27H30O16
Molecular Weight: 610.52
2. Physical and Chemical Properties
Physical Properties
- Appearance: Yellow crystalline powder
- Odor: Odorless natural flavonoid solid
- Solubility: Slightly soluble in cold H2O, freely soluble in hot H2O, CH3OH, C2H5OH and pyridine; insoluble in aliphatic hydrocarbons
- Melting Point: Decomposes above 188 °C without distinct melting point
- Hygroscopicity: Slightly hygroscopic under high humidity
- Aqueous Characteristic: Weakly acidic aqueous solution with strong antioxidant activity
Chemical Properties
- Molecular Structure: Flavonol glycoside composed of quercetin aglycone bound to rutinoside disaccharide moiety, multiple phenolic hydroxyl groups distributed on benzene rings
- Antioxidant Activity: Phenolic hydroxyl groups readily react with free radicals and oxygen, prone to oxidative browning under air exposure
- Acid-base Stability: Unstable under strong acid or alkaline heating, undergoes hydrolysis to produce quercetin and rutinose
- Thermal Stability: Stable below 60 °C; high temperature accelerates oxidation and glycosidic bond cleavage
- Photostability: Highly sensitive to UV light; long-term illumination causes fading and impurity generation
- Compatibility: Incompatible with strong oxidants, transition metal ions such as Fe3?, Cu2?
3. Main Application Fields
1. Health Food & Nutraceutical Raw Material (Core Application)
- Vascular-protecting nutritional additive, improves capillary toughness and reduces vascular fragility
- Natural antioxidant for anti-aging functional oral supplements
2. Pharmaceutical Excipient & API Intermediate
Raw material for venotonic medicines used to treat varicose veins and microcirculation disorders; stabilizer for herbal preparations
3. Cosmetic Active Ingredient
Antioxidant and anti-photoaging raw material for serum, facial mask and cream, scavenges skin free radicals
4. Biochemical Reference Standard
HPLC reference substance for flavonoid quantification in herbal extracts and plant raw materials
4. Quality Specification Table
| Test Item | Standard Index |
| CAS Number | 153-18-4 |
| Molecular Formula | C27H30O16 |
| Appearance | Yellow crystalline powder |
| HPLC Purity | Food Grade ≥95.0%; Pharma Grade ≥98.0% |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb1) | Food grade ≤10 ppm |
| Packaging | Nitrogen-purged amber aluminum foil vacuum bag / 25kg PE lined fiber drum |
| Storage Condition | Hermetically sealed in cool dark warehouse below 25 °C; strictly moisture-proof, light-proof and isolated from oxidants |
| Transportation Requirement | Oxidation-prone flavonoid powder, light-proof fully sealed packaging |
| Shelf Life | 24 months under nitrogen-sealed vacuum packaging |
Safety Warning
Low-toxic plant-derived flavonoid powder. Dust slightly irritates eyes and respiratory tract. Wear dust mask, chemical-resistant gloves and protective goggles in ventilated operating environment. Avoid long-term contact with air and light to prevent oxidative discoloration. Waste solid can be treated as biodegradable organic waste after harmless treatment
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