Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Choline chloride
1. Basic Information
Name: Choline chloride
Alias: 2-Hydroxy-N,N,N-trimethylethan-1-aminium chloride
CAS No.: 67-48-1
Molecular Formula: C5H14Cl1N1O1
Molecular Weight: 139.62
Category: Quaternary ammonium salt, feed additive, pharmaceutical raw material, biochemical reagent
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Slight fishy amine odor
- Solubility: Freely soluble in water, methanol, ethanol; insoluble in acetone, ether, aliphatic hydrocarbons
- Melting Range: 302–305 ℃ (decomposes)
- Hygroscopy: Extremely hygroscopic, quickly absorbs moisture and deliquesces in humid air
- Aqueous property: Aqueous solution neutral to weakly acidic, stable under pH 3–8
Chemical Properties
- Molecular structure: Trimethyl hydroxyethyl ammonium chloride quaternary ammonium salt
- Thermal stability: Stable below 200 ℃; high temperature decomposition releases trimethylamine irritating gas
- Compatibility: Compatible with most feed raw materials, neutral water-soluble reagents; incompatible with strong alkalis, anionic surfactants, heavy metal salts
- Hydroxyl reactivity: Terminal hydroxyl group can undergo esterification to synthesize choline ester derivatives
- Photostability: Stable under normal light; long-term intense UV irradiation turns faint yellow
3. Main Application Fields
1. Feed Additive (Core Application)
Essential nutrient for livestock, poultry and aquatic animals; promotes fat metabolism, prevents fatty liver, improves growth rate and egg production
2. Pharmaceutical Intermediate
Raw material for liver-protecting drugs, brain nutrition preparations; component of parenteral nutrition solutions
3. Deep Eutectic Solvent Raw Material
Compound with organic acids/polyols to prepare green biodegradable deep eutectic solvents
4. Biochemical Research Reagent
Cell culture medium additive, lipid metabolism research substrate
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 67-48-1 |
| Molecular Formula | C5H14Cl1N1O1 |
| Appearance | Uniform white crystal without deliquescent lumps |
| Purity | Feed grade ≥98.0%; Pharma grade ≥99.0% |
| Water Content (KF) | ≤0.50% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm (pharma grade) |
| Packaging | 25kg PE lined sealed woven bag / vacuum aluminum foil drum |
| Storage Condition | Hermetically sealed dry warehouse below 25 ℃, strictly moisture-proof, isolate alkaline chemicals |
| Transportation Requirement | Super hygroscopic quaternary ammonium solid, fully sealed moisture-proof packaging |
| Shelf Life | 24 months under nitrogen vacuum sealed storage |
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