Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
H-GLY-HYP-OH
1. Basic Information
Name: H-Gly-Hyp-OH
Alias: Glycyl-L-hydroxyproline, Glycyl trans-4-hydroxy-L-proline
CAS No.: 24587-32-4
Molecular Formula: C7H12N2O4
Molecular Weight: 188.18
Category: Dipeptide biochemical reagent, collagen detection standard, peptide synthetic intermediate
2. Physical and Chemical Properties
Physical Properties
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Freely soluble in water; slightly soluble in methanol; insoluble in ethanol, acetone, ether
- Melting Point: Decompose above 220 ℃
- Density (predicted): 1.44 g/cm3
- Hygroscopy: Slightly hygroscopic under high humidity
- Aqueous property: Amphoteric dipeptide, neutral aqueous solution, stable at pH 4–9
Chemical Properties
- Molecular structure: Dipeptide formed by glycine and trans-4-hydroxy-L-proline, contains amino, carboxyl, pyrrolidine ring and hydroxyl functional groups
- Peptide bond characteristic: Stable peptide bond under neutral condition; hydrolyze into two amino acids under strong acid/alkali heating
- Optical activity: Single L configuration, strict optical purity requirement for biochemical grade
- Thermal stability: Stable below 180 ℃; high temperature will trigger dehydration and peptide decomposition
- Photostability: Slightly light-sensitive, long-term UV irradiation turns faint yellow
- Compatibility: Compatible with aqueous buffer, low-carbon alcohols; incompatible with strong oxidants, concentrated strong acid
3. Main Application Fields
1. Biochemical Detection Standard (Core Application)
Standard substance for collagen content detection in food, cosmetics, tissue samples; marker of collagen metabolism
2. Peptide Synthetic Intermediate
Raw material for synthetic collagen-derived active peptides, skin care anti-aging peptide derivatives
3. Cell Culture & Pharmacology Research Reagent
Biochemical substrate for fibroblast culture, collagen synthesis mechanism research
4. Cosmetic Raw Material Auxiliary
Small molecule dipeptide additive for anti-aging, moisturizing skin care formulations
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 24587-32-4 |
| Molecular Formula | C7H12N2O4 |
| Appearance | Uniform white crystal without discoloration impurities |
| HPLC Purity | Biochemical Grade ≥99.0% |
| Specific Optical Rotation [α]D20 | ?45° ~ ?52° (water) |
| Water Content (KF) | ≤0.30% |
| Residue on Ignition | ≤0.10% |
| Single Maximum Unknown Impurity | ≤0.05% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | 1g/5g/10g vacuum aluminum foil bag, 25kg PE lined light-proof fiber drum |
| Storage Condition | Hermetically sealed cool dry warehouse 2–8 ℃, full light shielding, isolate moisture and oxidizing substances |
| Transportation Requirement | Light-sensitive dipeptide solid powder, moisture-proof & light-proof sealed packaging |
| Shelf Life | 36 months under nitrogen vacuum sealed low-temperature storage |
Safety Warning
Low-toxicity mild irritant dipeptide powder. Dust irritates eyes, nasal tract and respiratory mucosa; long-term skin contact may cause mild dry itching. All operations must be carried out in ventilated fume hood with dust-proof respirator and nitrile gloves. Laboratory and cosmetic raw material only, prohibited direct oral administration. Waste liquid neutralized before discharge; solid waste classified as biochemical hazardous waste disposed by licensed professional institutions.
...
Product
