Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Trimethylpyrazine
1. Basic Information
Name: Trimethylpyrazine
Alias: 2,3,5-Trimethylpyrazine
CAS No.: 14667-55-1
Molecular Formula: C7H10N2
Molecular Weight: 122.17
Category: Food flavor & fragrance raw material, heterocyclic fine chemical intermediate, tobacco flavor additive, analytical standard reagent
2. Physical and Chemical Properties
Physical Properties
- Appearance: Colorless to pale light yellow transparent liquid
- Odor: Strong nutty, roasted cocoa and caramel aroma, typical baked food fragrance
- Solubility: Miscible with ethanol, propylene glycol, acetone, vegetable oils; slightly soluble in cold water
- Boiling Point: 171–173 °C (760 mmHg)
- Density (20 °C): 0.970–0.976 g/cm3
- Refractive Index nD20: 1.503–1.507
- Hygroscopy: Non-hygroscopic
- Aqueous property: Weakly alkaline nitrogen heterocycle, stable in neutral cold water under ambient temperature
Chemical Properties
- Molecular structure: Pyrazine aromatic ring substituted with three methyl groups at positions 2,3,5; electron-rich aromatic heterocycle with active ring carbon sites
- Aroma characteristic: Maillard reaction product naturally formed during baking, roasting and high-temperature food processing
- Electrophilic substitution: Capable of halogenation, nitration and side-chain oxidation to produce pyrazine carboxylic acid derivatives
- Thermal stability: Stable under common food processing temperatures; only decomposes at temperatures above 220 °C
- Photostability: Slightly light-sensitive; long-term direct sunlight causes gradual yellowing
- Compatibility: Excellent miscibility with most flavor solvents, edible oils and cosmetic substrates; incompatible with concentrated strong acid and strong oxidants
3. Main Application Fields
1. Food Essence Raw Material (Core Application)
Widely applied in nut, chocolate, coffee, baked bread, popcorn, meat and caramel flavor formulations for candy, beverages, baked goods and savory seasonings
2. Tobacco Flavor Additive
Enhances roasted nut and sweet caramel notes in cigarette flavors, improves smoke richness
3. Pharmaceutical Heterocyclic Intermediate
Precursor for synthesizing pyrazine-series anti-tuberculosis and anti-inflammatory small-molecule drugs
4. Chromatography Reference Standard
HPLC/GC standard substance for flavor quantitative analysis and Maillard reaction research
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 14667-55-1 |
| Molecular Formula | C7H10N2 |
| Appearance | Clear colorless liquid without suspended impurities |
| GC Purity | Food Grade ≥99.0%, Synthetic Grade ≥98.5% |
| Water Content (KF) | ≤0.10% |
| Chroma (APHA) | ≤30 |
| Acid Value | ≤0.1 mgKOH/g |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Amber light-proof glass bottle; bulk 200kg sealed iron drum |
| Storage Condition | Hermetically sealed cool dry warehouse below 25 °C, light shielding, separate from strong oxidants and concentrated acid |
| Transportation Requirement | Slightly light-sensitive heterocyclic flavor liquid, standard sealed packaging, kept away from corrosive chemicals |
| Shelf Life | 24 months under nitrogen sealed storage |
...
Product
