Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Dextran Sulfate Sodium Salt
1. Basic Information
Name: Dextran Sulfate Sodium Salt
Alias: Sodium dextran sulfate
CAS No.: 9011-18-1
Molecular Formula: Variable polymer (general repeat unit formula: C6H7Na3O14S3)
Molecular Weight: Multiple specifications (5k, 10k, 50k, 500k, 1000k Da)
Category: Biochemical research reagent, anticoagulant raw material, cell culture additive, viral inhibitor, blood separation auxiliary
2. Physical and Chemical Properties
Physical Properties
- Appearance: White to off-white hygroscopic powder
- Odor: Odorless
- Solubility: Freely soluble in water; insoluble in ethanol, acetone, ether and other organic solvents
- Predicted Density: 1.6–1.8 g/cm3
- Hygroscopy: Strongly hygroscopic, readily absorbs moisture and agglomerates under high humidity
- Aqueous property: Aqueous solution shows weak acidity; stable in neutral aqueous environment; desulfation occurs under strong acid heating conditions
Chemical Properties
- Molecular structure: Linear dextran polysaccharide backbone modified with covalently bonded sulfate groups, sodium ions as counterions; anionic polyelectrolyte
- Biological activity: Inhibits viral adhesion to cell membranes; anticoagulant activity via interfering with blood coagulation factors; precipitates lipoproteins in serum
- Thermal stability: Stable below 80 °C; long-time boiling under acidic conditions leads to polysaccharide chain degradation and sulfate group loss
- Photostability: Moderately light-resistant; long-term intense UV exposure slightly reduces biological activity
- Compatibility: Compatible with neutral buffer salts and cell culture media; incompatible with strong acid, strong oxidants and cationic polymers
3. Main Application Fields
1. Biochemical & Cell Biology Research Reagent (Core Application)
Virus entry inhibitor for in vitro cell assays; lipoprotein precipitation reagent; additive to improve cell transfection efficiency
2. Pharmaceutical Raw Material
Low-molecular-weight grade for anticoagulant, anti-lipidemic pharmaceutical formulations
3. Biomedical Separation Auxiliary
Component for density gradient separation medium of blood cells and immune cells
4. Food & Cosmetic Stabilizer
Anionic thickening stabilizer for cosmetic serum and functional food emulsions
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 9011-18-1 |
| Appearance | Uniform white powder without yellow discoloration |
| Molecular Weight | Customized grades: 5k/10k/50k/500k/1000k Da |
| Sulfur Content | 16–19% |
| Water Content (KF) | ≤5.0% |
| Residue on Ignition | 22–28% |
| Endotoxin | ≤0.1 EU/mg (Cell Culture Grade) |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Light-proof nitrogen-filled aluminum foil vacuum bag; bulk 25kg PE lined fiber drum |
| Storage Condition | Hermetically sealed cool dry warehouse at 2–25 °C, full light shielding, strictly isolated from humid air |
| Transportation Requirement | Highly hygroscopic biochemical polymer powder, moisture-proof sealed packaging, separated from acidic hazardous goods |
| Shelf Life | 24 months under intact nitrogen vacuum sealed storage |
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