Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Azamethiphos
1. Basic Information
Name: Azamethiphos
Alias: S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate, Azamethiphos technical, Salmosan active ingredient
CAS No.: 35575-96-3
EINECS: 252-626-0
Molecular Formula: C?H??ClN?O?PS
Molecular Weight: 324.68
Category: Organothiophosphate insecticide, public health pest control agent, aquaculture sea lice treatment pesticide, pesticide reference standard
Azamethiphos chemical structure
2. Physical and Chemical Properties
Physical Properties
- Appearance: White to pale light yellow crystalline powder
- Odor: Faint mild organophosphorus odor
- Solubility: 1.27 g/L in water at 20 °C; slightly soluble in methanol, chloroform, acetone; insoluble in aliphatic alkanes and ether
- Melting Point: 88–92 °C
- Predicted Boiling Point: 428.8 ± 55.0 °C (thermal decomposition)
- Predicted Density: 1.566 g/cm3
- Vapor Pressure: 4.9 × 10?? Pa (20 °C)
- Hygroscopy: Slightly hygroscopic, sensitive to high humidity
- Aqueous property: Neutral organophosphorus heterocycle; slow hydrolysis under strong acid/alkali heating conditions
Chemical Properties
- Molecular structure: Chlorinated oxazolopyridinone heterocycle linked with O,O-dimethyl phosphorothioate via thiomethylene bridge; acetylcholinesterase inhibitor active scaffold
- Insecticidal mechanism: Inhibits insect acetylcholinesterase, disrupts nerve signal transmission to cause knockdown and death of target pests
- Hydrolysis stability: Stable under neutral cool water; accelerated degradation in high-temperature alkaline water
- Photostability: Light-sensitive; UV exposure accelerates decomposition and reduces biological activity
- Thermal stability: Stable below 80 °C; above melting point decomposes to release toxic phosphorus, chloride and sulfur-containing fumes
- Compatibility: Compatible with most pesticide emulsifiers and bait substrates; incompatible with strong oxidants, concentrated alkaline solutions and copper metal ions
3. Main Application Fields
1. Aquaculture Sea Lice Control (Core Application)
Active ingredient of Salmosan bath treatment for farmed salmon, controls parasitic sea lice on marine fish
2. Public Health Sanitary Insecticide
Used in fly bait formulations for livestock farms, food factories, restaurants; controls houseflies, cockroaches and other sanitary pests with long residual effect
3. Veterinary & Livestock Pest Control
Eliminates parasitic flies and arthropods in breeding houses, low acute toxicity to mammals under standard dosage
4. Pesticide Detection Reference Standard
HPLC/GC reference substance for residual quantification of organophosphorus pesticides in aquatic products and environmental water samples
4. Quality Specification Table
| Test Item | Standard Specification |
| CAS Number | 35575-96-3 |
| Molecular Formula | C?H??ClN?O?PS |
| Appearance | Uniform off-white crystalline powder without dark discoloration |
| HPLC Purity | Technical Pesticide Grade ≥98.0%, Reference Standard Grade ≥99.5% |
| Melting Point | 88–92 °C |
| Water Content (KF) | ≤0.20% |
| Free Phosphate Impurity | ≤0.15% |
| Single Unknown Impurity | ≤0.10% |
| Heavy Metals (Pb) | ≤10 ppm |
| Packaging | Light-proof nitrogen-filled aluminum foil vacuum bag; bulk 25kg PE lined sealed fiber drum |
| Storage Condition | Hermetically sealed cool dry warehouse at 2–8 °C, full light shielding, isolated from humid air, food, oxidants and alkaline chemicals |
| Transportation Requirement | Toxic light-sensitive pesticide solid, Class 6 toxic goods transport standard, strictly separated from food, drinking water and aquatic products |
| Shelf Life | 24 months under intact nitrogen vacuum sealed packaging |
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