Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
2',4'-Dichloroacetophenone
1. Basic Product Information
Product Name: 2',4'-Dichloroacetophenone
CAS Number: 2234-16-4
Molecular Formula: C8H6Cl2O
Molecular Weight: 189.04
Synonyms: 1-(2,4-Dichlorophenyl)ethan-1-one
Product Category: Aromatic fine chemical, pharmaceutical & pesticide intermediate, organic synthesis raw material
2. Physical and Chemical Properties
Physical Parameters
- Appearance: White to pale yellow crystalline solid
- Odor: Mild aromatic ketone odor
- Solubility: Soluble in ethanol, ethyl acetate, chloroform, DMF, toluene; slightly soluble in hot methanol; insoluble in cold water and petroleum ether
- Melting Point: 32–35 °C
- Density (20 °C): 1.32 g/cm3
- Hygroscopicity: Non-hygroscopic under sealed storage
- Aqueous Stability: Stable in neutral cold water
Chemical Characteristics
- Molecular Structure: Benzene ring substituted with acetyl group at C1, two chlorine atoms at ortho and para positions; contains active carbonyl and aryl chloride functional groups
- Reactivity of Carbonyl Group: Supports aldol condensation, imination, reduction, halogenation for molecular derivatization
- Aromatic Ring Modification: Aryl chloride can participate in Suzuki coupling, hydrolysis and other cross-coupling reactions
- Photostability: Slightly light-sensitive; long-term UV exposure generates trace dechlorination impurities and darkens the product
- Thermal Stability: Stable below 30 °C; slow decomposition occurs above 100 °C, releasing irritating hydrogen chloride fumes
- Chemical Compatibility: Compatible with anhydrous polar aprotic solvents; incompatible with strong oxidants and concentrated strong alkali
3. Main Application Fields
- Core Application: Pharmaceutical Synthetic Intermediate
Key building block for anti-inflammatory, antibacterial and antiparasitic APIs; used to construct halogenated aromatic heterocyclic skeletons via condensation and cyclization reactions - Pesticide & Fungicide Raw Material
Precursor for high-efficiency halogenated bactericides and insecticides for crop protection - Laboratory Organic Synthesis Reagent
Standard substrate for cross-coupling, carbonyl condensation and aromatic functionalization research - Azo Dye Precursor
Raw material for high light-fastness textile azo dyes and color fixing agents
4. Platform Category & Product Group Selection Guide
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Organic Intermediates
Reason: It is a halogenated aromatic ketone fine chemical intermediate, suitable for general organic intermediate classification.
2) English Product Group Dropdown Options
Recommended Selection: Basic Organic Chemicals
Do not select Pharmaceutical Chemicals; it is a general synthetic intermediate rather than human medicine bulk drug.
3. Standard Foreign Trade Packaging Specification
1kg aluminum foil vacuum bag for lab samples; 25kg fiber drum lined with double PE plastic bags for bulk orders; customized packaging specifications are available upon request
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 2234-16-4 |
| Molecular Formula | C8H6Cl2O |
| Appearance | Uniform white to pale yellow crystal without dark brown impurities |
| HPLC Purity | Pharma Intermediate Grade ≥99.0%, Industrial Grade ≥98.5% |
| Melting Point | 32–35 °C |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.50% |
| Heavy Metals (Pb) | ≤10 ppm |
| Standard Storage Package | Light-proof nitrogen-sealed aluminum foil vacuum bag, 25kg PE lined fiber drum |
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