Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Octreotide Acetate
1. Basic Product Information
Product Name: Octreotide Acetate
CAS Number: 83150-76-9
Molecular Formula: C49H66N10O10S2·2C2H4O2
Molecular Weight: 1139.35
Chemical Name: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2-7)-disulfide, acetate salt
Product Category: Synthetic Peptide API, Somatostatin Analog, Pharmaceutical Peptide Raw Material, Biochemical Research Reagent
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White to off-white lyophilized crystalline powder
- Odor: Odorless
- Solubility: Freely soluble in water, dilute acetic acid; soluble in methanol; slightly soluble in ethanol; insoluble in acetone, chloroform, petroleum ether
- Melting Point: 167–174 °C
- Optical Rotation: -15° ~ -10° (c=0.5, H?O)
- Hygroscopicity: Highly hygroscopic, sensitive to moisture in air
- Aqueous Stability: Stable under weak acidic conditions; hydrolyzes rapidly under alkaline or high-temperature environment
Chemical Characteristics
- Molecular Structure: Cyclic octapeptide with disulfide bond, two acetate counterions, multiple amino, hydroxyl and amide functional groups
- Pharmacological Mechanism: Synthetic long-acting somatostatin analog, potent inhibitor of growth hormone, insulin, glucagon and gastrointestinal hormone secretion
- Hydrolysis Risk: Disulfide bond and peptide bonds break under high temperature, strong alkali or long-term exposure to moisture, leading to loss of biological activity
- Photostability: Light-sensitive; UV irradiation triggers peptide degradation and discoloration
- Thermal Stability: Stable below 40 °C; irreversible decomposition above 80 °C
- Chemical Compatibility: Compatible with weak acidic aqueous buffers; incompatible with alkaline substances, strong oxidants, heavy metal ions
3. Main Application Fields
- Core Application: Human Pharmaceutical API
Approved therapeutic raw material for injection formulations; indicated for acromegaly, carcinoid tumor flushing and severe diarrhea, VIPoma watery diarrhea, acute variceal hemorrhage - Peptide Drug Intermediate
Key raw material for sustained-release microsphere depot formulations for long-acting monthly injection - Biomedical Laboratory Research Reagent
Standard somatostatin analog for endocrine, tumor cell proliferation and gastrointestinal pharmacology research - HPLC Reference Standard
Certified reference substance for related substance testing of octreotide acetate bulk drugs and injections
4. Platform Category & Product Group Selection Guide
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Pharmaceutical Intermediates
Reason: It is a prescription human pharmaceutical peptide API, classified under pharmaceutical intermediates; not veterinary or water treatment chemical categories.
2) English Product Group Dropdown Options
Recommended Selection: Pharmaceutical Chemicals
Do NOT select Basic Organic Chemicals; this product is regulated human pharmaceutical raw material, which matches the pharmaceutical chemical grouping.
3. Standard Foreign Trade Packaging Specification
5mg/10mg/50mg glass vial for lab research samples; 1g/5g aluminum foil vacuum bag, 25kg fiber drum lined with double PE inner bags for bulk API orders; customized sterile packaging available for pharmaceutical production
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 83150-76-9 |
| Molecular Formula | C49H66N10O10S2·2C2H4O2 |
| Appearance | Uniform white crystalline powder without yellow discoloration |
| HPLC Purity | Pharma API Grade ≥98.5%, Reference Standard ≥99.5% |
| Optical Rotation | -15° ~ -10° (c=0.5, H?O) |
| Water Content (KF Method) | ≤0.50% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Peptide Impurities | ≤0.50% |
| Heavy Metals (Pb) | ≤10 ppm |
| Endotoxin | ≤0.1 EU/mg (Injection Grade) |
| Standard Storage Package | Light-proof nitrogen-sealed aluminum foil vacuum bag, stored in low-temperature sealed container |
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