Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Tropinone
1. Basic Product Information
Product Name: Tropinone
CAS Number: 532-24-1
Molecular Formula: C8H13NO
Molecular Weight: 139.19
Synonyms: 8-Methyl-8-azabicyclo[3.2.1]octan-3-one
Product Category: Tropane alkaloid intermediate, pharmaceutical synthetic intermediate, organic synthesis raw material
2. Physical and Chemical Properties
Physical Indicators
- Appearance: Off-white to light yellow crystalline solid
- Odor: Faint characteristic alkaloid odor
- Solubility: Soluble in ethanol, methanol, chloroform, dichloromethane; soluble in hot water; slightly soluble in cold water, insoluble in aliphatic hydrocarbons
- Melting Point: 40–44 °C
- Density (20 °C): 1.07 g/cm3
- Hygroscopicity: Slightly hygroscopic under high humidity environment
- Aqueous Stability: Stable under neutral and weak acidic conditions; prone to side reactions under strong alkaline heating
Chemical Characteristics
- Molecular Structure: Bicyclic tropane skeleton with tertiary amine and ketone functional group at C3 position
- Core Synthetic Function: Key precursor for synthesizing tropane alkaloid APIs such as atropine, scopolamine, cocaine derivatives and anesthetic drugs
- Ketone Reactivity: The carbonyl group can undergo reduction, reductive amination, condensation and halogenation to construct multiple tropane drug skeletons
- Photostability: Light-sensitive; long-term UV exposure causes yellow discoloration and trace degradation
- Thermal Stability: Stable below 35 °C; slow decomposition above 60 °C, releasing irritating amine volatile fumes
- Chemical Compatibility: Compatible with anhydrous polar aprotic solvents; incompatible with strong oxidants, concentrated strong acids and strong alkalis
3. Main Application Fields
- Core Application: Pharmaceutical Tropane Alkaloid Intermediate
Exclusive building block for manufacturing anticholinergic APIs, mydriatic drugs, anti-spasmodic medicines and local anesthetics; widely used in global pharmaceutical production lines - Natural Product Synthesis Research Reagent
Standard substrate for tropane alkaloid total synthesis methodology research in organic chemistry laboratories - Fine Chemical Derivatization Raw Material
Precursor for chiral amine ligands and organic catalyst synthesis
4. Platform Category & Product Group Selection Guide
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Pharmaceutical Intermediates
Reason: It is a core bicyclic intermediate for human anticholinergic pharmaceutical APIs, classified as pharmaceutical intermediate.
2) English Product Group Dropdown Options
Recommended Selection: Pharmaceutical Chemicals
Do NOT select Basic Organic Chemicals; this product is dedicated to human pharmaceutical raw material synthesis, matching pharmaceutical chemical grouping.
3. Standard Foreign Trade Packaging Specification
1kg aluminum foil vacuum bag for lab samples; 25kg fiber drum lined with double PE inner bags for bulk industrial orders; nitrogen-sealed light-proof packaging, customized specifications available
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 532-24-1 |
| Molecular Formula | C8H13NO |
| Appearance | Uniform off-white crystalline solid without deep yellow impurities |
| HPLC Purity | Pharma Intermediate Grade ≥99.0%, Reference Standard ≥99.8% |
| Melting Point | 40–44 °C |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Standard Storage Package | Light-proof nitrogen-sealed aluminum foil vacuum bag, 25kg PE lined fiber drum |
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