Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Tetracaine
1. Basic Product Information
Product Name: Tetracaine
CAS Number: 94-24-6
Molecular Formula: C15H24N2O2
Molecular Weight: 264.36
Synonyms: 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine
Product Category: Local anesthetic pharmaceutical API, ester-type anesthetic intermediate, clinical pharmaceutical raw material
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White to off-white crystalline powder
- Odor: Odorless, slightly bitter taste
- Solubility: Soluble in ethanol, methanol, chloroform and ether; slightly soluble in hot water; barely soluble in cold water
- Melting Point: 41–46 °C
- Density (20 °C): 1.04 g/cm3
- Hygroscopicity: Slightly hygroscopic under high humidity environment
- Aqueous Stability: Stable under neutral and weakly acidic conditions; susceptible to ester hydrolysis under heated alkaline aqueous solution to generate p-butylaminobenzoic acid byproducts
Chemical Characteristics
- Molecular Structure: Para-aminobenzoic acid ester derivative with butylamino substituent and dimethylaminoethyl ester side chain
- Core Functional Mechanism: Long-acting ester local anesthetic; blocks sodium ion channels of nerve cell membrane to inhibit nerve signal transmission, widely used for surface anesthesia of mucous membranes
- Photostability: Light-sensitive; long-term UV irradiation triggers discoloration and reduces anesthetic activity
- Thermal Stability: Stable below 40 °C; prolonged heating above 60 °C accelerates ester hydrolysis degradation
- Chemical Compatibility: Compatible with anhydrous polar organic solvents; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
- Core Application: Human Local Anesthetic API
Active raw material for ophthalmic, otolaryngologic and mucosal surface anesthetic formulations; applied for eye drops, nasal sprays and topical anesthesia preparations - Pharmaceutical Synthetic Intermediate
Precursor for manufacturing tetracaine hydrochloride injection raw material via salt-forming reaction - Biochemical Research Reagent
Nerve channel inhibitor standard for neuroscience and anesthesia mechanism laboratory research
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Pharmaceutical Intermediates
Reason: Ester-type local anesthetic parent base for clinical mucosal anesthetic drug synthesis
2) English Product Group Dropdown Options
Recommended Selection: Pharmaceutical Chemicals
Do NOT classify as general industrial chemicals; it is controlled clinical anesthetic raw material
3. Standard Foreign Trade Packaging Specification
1g / 5g nitrogen-sealed amber glass vials for reference standards; 1kg aluminum foil vacuum bags for pharmaceutical pilot batches; 25kg double PE-lined lightproof fiber drums for GMP bulk production
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 94-24-6 |
| Molecular Formula | C15H24N2O2 |
| Appearance | Uniform white crystalline powder without yellow impurities |
| HPLC Purity | Pharma Grade ≥99.0%, Reference Standard ≥99.8% |
| Melting Point | 41–46 °C |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Standard Storage Package | Lightproof nitrogen-filled vacuum aluminum foil bag, cool low-temperature warehouse storage |
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