Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Minoxidil
1. Basic Product Information
Product Name: Minoxidil
CAS Number: 38304-91-5
Molecular Formula: C9H15N5O
Molecular Weight: 209.25
Synonyms: 6-(1-Piperidinyl)-2,4-pyrimidinediamine, U-10858
Product Category: Human pharmaceutical API, hair growth active ingredient, cardiovascular drug intermediate, cosmetic raw material
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Solubility: Soluble in ethanol, methanol, propylene glycol; slightly soluble in water; insoluble in ether, benzene and aliphatic hydrocarbons
- Melting Point: 248–252 °C (decomposes)
- Density (20 °C): 1.32 g/cm3
- Hygroscopicity: Slightly hygroscopic under high humidity air
- Aqueous Stability: Stable under neutral and weakly acidic aqueous environments; slow hydrolysis occurs under prolonged heating with strong alkali
Chemical Characteristics
- Molecular Structure: Pyrimidine heterocyclic compound with two amino groups and one piperidinyl substituent on pyrimidine ring
- Core Functional Mechanism: Potent potassium channel opener; dilates peripheral blood vessels to improve scalp blood circulation and stimulate hair follicle regeneration; originally developed as oral antihypertensive drug, now widely used for topical alopecia treatment
- Photostability: Light-sensitive; long-term UV exposure causes slight yellow discoloration and reduces biological activity
- Thermal Stability: Stable below 200 °C; thermal decomposition above melting point releases irritant nitrogen-containing heterocyclic fumes
- Chemical Compatibility: Compatible with polar protic solvents and cosmetic excipients; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
- Core Application: Topical Hair Loss Treatment API
Main active raw material for anti-hair loss sprays, lotions and tinctures to treat androgenetic alopecia and alopecia areata - Cardiovascular Pharmaceutical Intermediate
Raw material for oral antihypertensive formulations for severe refractory hypertension treatment - Cosmetic Functional Raw Material
Approved hair care active ingredient added in professional hair growth serums and scalp care products - Biochemical Research Reagent
Potassium channel modulator standard for cardiovascular and dermatology mechanism research
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Pharmaceutical Intermediates
Reason: Pyrimidine heterocyclic API used in dermatological hair care and hypertension pharmaceutical preparations
2) English Product Group Dropdown Options
Recommended Selection: Pharmaceutical Chemicals
Do NOT classify as general industrial chemicals; it is clinical human-use active pharmaceutical ingredient
3. Standard Foreign Trade Packaging Specification
1g / 5g nitrogen-sealed amber glass vials for reference standards; 1kg aluminum foil vacuum bags for pharmaceutical pilot synthesis; 25kg double PE-lined light-proof fiber drums for GMP bulk production
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 38304-91-5 |
| Molecular Formula | C9H15N5O |
| Appearance | Uniform white crystalline powder free of yellow or brown impurities |
| HPLC Purity | Pharma Grade ≥99.0%, Reference Standard ≥99.8% |
| Melting Point | 248–252 °C (decomposes) |
| Water Content (KF Method) | ≤0.30% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Standard Storage Package | Lightproof nitrogen-filled vacuum aluminum foil bag, cool dry warehouse storage |
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