Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Cytosine
1. Basic Product Information
Product Name: Cytosine
CAS Number: 71-30-7
Molecular Formula: C4H5N3O
Molecular Weight: 111.10
Synonyms: 4-Amino-2-hydroxypyrimidine, 2-Oxy-4-aminopyrimidine
Product Category: Biochemical raw material, nucleic acid monomer intermediate, cell culture medium additive, chromatographic standard reagent, pharmaceutical heterocyclic precursor
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White crystalline powder
- Odor: Odorless
- Solubility: Sparingly soluble in cold water, freely soluble in hot water; slightly soluble in ethanol; insoluble in ether, benzene and aliphatic hydrocarbons
- Melting Point: Over 300 °C (decomposes without melting clearly)
- Density (20 °C): 1.55 g/cm3
- Hygroscopicity: Non-hygroscopic under sealed dry storage
- Aqueous Stability: Stable under neutral and weakly acidic aqueous solutions; slow deamination degradation occurs under strong alkaline heating conditions
Chemical Characteristics
- Molecular Structure: Pyrimidine heterocyclic base with amino group at 4-position and carbonyl group at 2-position, one of four core DNA/RNA nitrogenous bases
- Core Functional Mechanism: Fundamental building block of nucleic acids; forms complementary hydrogen bonds with guanine during DNA replication and transcription; raw material for synthesizing cytidine, cytidine monophosphate and nucleotide anti-viral intermediates
- Photostability: Mildly light-sensitive; long-term UV irradiation triggers slight discoloration
- Thermal Stability: Stable below 220 °C; high-temperature decomposition releases irritating nitrogen-containing heterocyclic volatile fumes
- Chemical Compatibility: Compatible with inorganic salt buffers and most biotech medium raw materials; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
- Core Application: Biochemical Nucleic Acid Raw Material
Key starting material for nucleoside and nucleotide synthesis for gene research, PCR reagent and nucleic acid detection kits - Pharmaceutical Synthetic Intermediate
Precursor for manufacturing anti-viral, anti-tumor nucleotide pharmaceutical APIs - Cell Culture & Fermentation Reagent
Medium additive for microbial strain fermentation and eukaryotic cell culture - Laboratory Chromatography Standard
Reference standard for HPLC nucleic acid base detection and molecular biology experiment calibration
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Biochemical Reagents
Reason: Pyrimidine nucleic acid base used in biotech, molecular biology and pharmaceutical synthesis industries
2) English Product Group Dropdown Options
Recommended Selection: Basic Organic Chemicals
Do NOT solely classify as pharmaceutical chemicals; it is universal biochemical standard raw material
3. Standard Foreign Trade Packaging Specification
1g / 5g nitrogen-sealed amber glass vials for reference standards; 1kg aluminum foil vacuum bags for biotech batches; 25kg double PE-lined lightproof fiber drums for bulk industrial orders
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 71-30-7 |
| Molecular Formula | C4H5N3O |
| Appearance | Uniform white crystalline powder without brown impurities |
| HPLC Purity | Biochemical Grade ≥99.5%, Reference Standard ≥99.8% |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Ash Content | ≤0.05% |
| Standard Storage Package | Lightproof nitrogen-filled vacuum aluminum foil bag, cool dry warehouse storage |
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