Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
2-Phenylacetamide
1. Basic Product Information
Product Name: 2-Phenylacetamide
CAS Number: 103-81-1
Molecular Formula: C8H9NO
Molecular Weight: 135.16
Synonyms: Phenylacetamide, Benzylcarboxamide
Product Category: Pharmaceutical synthetic intermediate, fine aromatic chemical, organic synthesis raw material
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Solubility: Soluble in ethanol, methanol, chloroform; slightly soluble in hot water; insoluble in cold water, ether and aliphatic hydrocarbons
- Melting Point: 156–159 °C
- Density (20 °C): 1.12 g/cm3
- Hygroscopicity: Non-hygroscopic under sealed dry storage
- Aqueous Stability: Stable in neutral and weakly acidic aqueous solutions; amide hydrolysis occurs upon long-time heating under strong alkaline conditions
Chemical Characteristics
- Molecular Structure: Benzyl group linked with acetamide structure, aromatic amide compound
- Core Functional Mechanism: Key intermediate for synthesizing penicillin, anti-inflammatory and central nervous system pharmaceutical APIs; undergoes hydrolysis, substitution and cyclization reactions to generate multiple fine chemical derivatives
- Photostability: Light-sensitive; long-term UV irradiation causes slight yellow discoloration
- Thermal Stability: Stable below 120 °C; high-temperature heating accelerates amide bond cleavage degradation
- Chemical Compatibility: Compatible with anhydrous polar organic solvents; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
- Core Application: Pharmaceutical Synthetic Intermediate
Starting material for synthesizing penicillin series antibiotics and phenylacetamide derivative drugs - Fine Chemical Synthetic Raw Material
Precursor for manufacturing aromatic amide dyes, pesticide intermediates and flavor ester derivatives - Biochemical Laboratory Reagent
Amide substrate standard for amidase enzyme activity research
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Pharmaceutical Intermediates
Reason: Aromatic amide intermediate for antibiotic and fine chemical synthesis
2) English Product Group Dropdown Options
Recommended Selection: Basic Organic Chemicals
Do NOT solely classify as pharmaceutical finished APIs; it is industrial synthetic intermediate
3. Standard Foreign Trade Packaging Specification
1kg nitrogen-sealed amber glass vials for reference standards; 1kg aluminum foil vacuum bags for pilot synthesis batches; 25kg double PE-lined lightproof fiber drums for bulk orders
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 103-81-1 |
| Molecular Formula | C8H9NO |
| Appearance | Uniform white crystalline powder without brown impurities |
| HPLC Purity | Pharma Grade ≥99.0%, Reference Standard ≥99.8% |
| Melting Point | 156–159 °C |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Standard Storage Package | Lightproof nitrogen-filled vacuum aluminum foil bag, cool dry warehouse storage |
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