Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Melatonin
1. Basic Product Information
Product Name: Melatonin
CAS Number: 73-31-4
Molecular Formula: C13H16N2O2
Molecular Weight: 232.28
Synonyms: N-Acetyl-5-methoxytryptamine, Melatonine
Product Category: Biochemical raw material, sleep-aid functional food additive, pharmaceutical API, cell culture reagent, anti-oxidant skincare active ingredient
2. Physical and Chemical Properties
Physical Indicators
- Appearance: White to pale off-white crystalline powder
- Odor: Odorless
- Solubility: Soluble in ethanol, methanol, DMSO, chloroform; slightly soluble in hot water; insoluble in cold water and aliphatic hydrocarbons
- Melting Point: 116–119 °C
- Density (20 °C): 1.18 g/cm3
- Hygroscopicity: Non-hygroscopic under sealed dry storage
- Aqueous Stability: Unstable in aqueous solution; prone to oxidation and discoloration under UV light, high temperature or alkaline environment
Chemical Characteristics
- Molecular Structure: Indole heterocyclic amide compound, containing methoxy group and acetylaminoethyl side chain
- Core Functional Mechanism: Neuroendocrine hormone secreted by human pineal gland; regulates circadian rhythm, improves sleep quality; possesses anti-oxidation, immune regulation and anti-aging effects
- Photostability: Extremely light-sensitive; light exposure triggers indole ring oxidation to form dark brown impurities and reduce activity
- Thermal Stability: Stable below 60 °C; heating above 90 °C accelerates amide degradation and oxidation
- Chemical Compatibility: Compatible with anhydrous protic solvents and neutral vitamin excipients; incompatible with strong oxidants, concentrated strong alkalis and heavy metal ions
3. Main Application Fields
- Core Application: Functional Food & Health Supplement Raw Material
Sleep-improving additive for sleep-aid tablets, oral liquids and sports nutrition supplements - Pharmaceutical Raw Material
API for sleep regulation, anti-depressant and immune-regulating compound preparations - Cell Culture Biochemical Reagent
Medium additive for mammalian cell culture to reduce oxidative stress damage of cells - High-End Anti-Aging Cosmetic Raw Material
Anti-oxidation, anti-photoaging skincare additive to alleviate skin oxidative damage caused by ultraviolet rays
4. Platform Category & Product Group Guidance
1) Domestic B2B Platform Category
Recommended Path: Organic Intermediates / Biochemical Reagents
Reason: Indole heterocyclic biochemical raw material widely used in health food, pharmaceutical and biotech industries
2) English Product Group Dropdown Options
Recommended Selection: Basic Organic Chemicals
Do NOT solely classify as pharmaceutical finished APIs; it is food and biotech grade biochemical intermediate
3. Standard Foreign Trade Packaging Specification
1g nitrogen-sealed amber glass vials for reference standards; 1kg vacuum aluminum foil bags for pilot batches; 25kg double PE-lined fully lightproof fiber drums for bulk production
5. Quality Specification Table
| Test Item | Standard Requirement |
| CAS Number | 73-31-4 |
| Molecular Formula | C13H16N2O2 |
| Appearance | Uniform white crystalline powder without brown impurities |
| HPLC Purity | Health Food Grade ≥99.0%, Reference Standard ≥99.8% |
| Water Content (KF Method) | ≤0.20% |
| Single Unknown Impurity | ≤0.10% |
| Total Related Substances | ≤0.40% |
| Heavy Metals (Pb) | ≤10 ppm |
| Ash Content | ≤0.05% |
| Standard Storage Package | Lightproof nitrogen-filled vacuum aluminum foil bag, cool dark warehouse storage |
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